Neutrophil Marker Activators, as the name suggests, are molecules that stimulate or enhance the expression of specific markers on neutrophils, which are a type of white blood cell crucial for the body's innate immune response. Neutrophils are the most abundant type of white blood cells in the human circulatory system and play a pivotal role in defending the body against bacterial infections. These cells contain granules filled with potent enzymes and antimicrobial substances. When neutrophils are activated, they exhibit changes on their cell surface, and these changes can be identified through specific markers. The markers are essentially proteins or glycoproteins found on the surface of neutrophils and can provide valuable insights into the functional status and activation state of these cells.
Neutrophil Marker Activators can either be endogenous or exogenous molecules. Endogenous activators are naturally produced within the body and include cytokines, chemokines, and other signaling molecules. When an infection or tissue damage occurs, these molecules are released to recruit and activate neutrophils, ensuring a rapid immune response. Exogenous activators, on the other hand, can be introduced into the system, often for research purposes, to study neutrophil behavior, dynamics, and interactions with other cells. Commonly used exogenous activators include bacterial products or specific agents that mimic the body's natural signaling molecules. Both types of activators help scientists gain a better understanding of neutrophil biology, their role in the immune system, and their interactions with various pathogens. Through the study of these activators, a deeper insight into the complex processes of inflammation, immune cell recruitment, and cellular communication can be obtained.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA can activate the protein kinase C pathway in cells. This activation may lead to the upregulation of certain proteins associated with neutrophils. | ||||||
N-Formyl-L-methionine | 4289-98-9 | sc-215458 sc-215458A | 10 mg 250 mg | $25.00 $42.00 | ||
It is a compound that can activate and attract neutrophils to sites of infection or injury, potentially influencing protein expression. | ||||||
LTB4 (Leukotriene B4) | 71160-24-2 | sc-201043 | 50 µg | $374.00 | 4 | |
Leukotriene B4 is known to be a powerful chemoattractant and activator for neutrophils. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to modulate neutrophil function and may influence the expression of associated proteins. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Niacin has been linked with the modulation of neutrophil activity, potentially affecting the expression of neutrophil-related proteins. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $111.00 $357.00 | 8 | |
Thalidomide has anti-inflammatory properties and can influence neutrophil functions. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
Aspirin can modulate the functions of neutrophils and might influence the expression of certain proteins. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone, a corticosteroid, can affect neutrophil responses and thus, potentially, the proteins associated with them. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to have effects on neutrophil activity and might influence the expression of associated proteins. | ||||||