Date published: 2026-1-31

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Neutrophil Marker Inhibitors

Neutrophil Marker Inhibitors belongs to a distinctive category of compounds designed to modulate specific biological processes involving neutrophils. Neutrophils are a type of white blood cell, a fundamental component of the immune system responsible for combating infections and participating in various inflammatory reactions. Neutrophil marker inhibitors are meticulously crafted molecules that interact with specific molecular markers present on the surface of neutrophils or within their signaling pathways. These markers play crucial roles in guiding neutrophil activation, migration, and adhesion, all of which are integral to their immune response functions. By targeting these markers, inhibitors can effectively dampen or modulate the actions of neutrophils, leading to a controlled and measured impact on the immune and inflammatory responses. The chemical structures of neutrophil marker inhibitors are designed with precision to facilitate binding interactions with the identified markers, thereby interrupting or altering the intricate signaling cascades that drive neutrophil behavior. These inhibitors can encompass a diverse range of chemical moieties, including small organic molecules, peptides, or even larger biologics. What unites them is their capacity to selectively interact with the target markers, exerting a regulatory influence over the neutrophils' actions without completely halting their functions. Due to the complex and nuanced nature of neutrophil behavior, these inhibitors are subject to rigorous design and optimization processes to ensure their specificity and efficacy. Ongoing research in this field continually refines our understanding of neutrophil biology and aids in the development of novel inhibitor compounds, paving the way for potential applications in various contexts where finely-tuned modulation of immune responses is desired.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SB 225002

182498-32-4sc-202803
sc-202803A
1 mg
5 mg
$36.00
$102.00
2
(1)

Inhibits CXCR2 receptor, reducing neutrophil recruitment and migration.

Reparixin

266359-83-5sc-507446
5 mg
$78.00
(0)

Binds to CXCR1 and CXCR2, hindering neutrophil chemotaxis and inflammation.

Filgotinib

1206161-97-8sc-507393
10 mg
$150.00
(0)

JAK1 inhibitor, indirectly affecting neutrophil functions in inflammation.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

Blocks NF-κB activation, leading to decreased pro-inflammatory cytokines.

[4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone

873225-46-8sc-503387
10 mg
$430.00
(0)

Inhibits IκB kinase, downregulating NF-κB pathway and inflammatory response.

BAY 11-7085

196309-76-9sc-202490
sc-202490A
10 mg
50 mg
$124.00
$526.00
55
(2)

Suppresses IκBα phosphorylation, reducing NF-κB activation and inflammation.

Tauroursodeoxycholic Acid, Sodium Salt

14605-22-2sc-281165
1 g
$644.00
5
(1)

Modulates ER stress, impacting neutrophil apoptosis and inflammation.

PI 3-Kγ Inhibitor

648450-29-7sc-203191
5 mg
$76.00
(0)

JNK inhibitor, affecting neutrophil chemotaxis, adhesion, and inflammation.

R788

901119-35-5sc-364597
sc-364597A
2 mg
50 mg
$405.00
$4000.00
2
(0)

SYK kinase inhibitor, potentially modulating neutrophil activation responses.