NECAP 2 Activators
NECAP 2 Activators comprise a diverse group of chemical compounds that can enhance the functional activity of NECAP 2 through various specific signaling pathways. For instance, N6-cyclopentyladenosine (CPA) and Forskolin influence cAMP levels, a factor influencing clathrin-mediated endocytosis, a process involving NECAP 2. By altering cAMP levels, these compounds could indirectly enhance NECAP 2 activity. Similarly, PKC 412 and Calphostin C inhibit protein kinase C, influencing the phosphorylation state of proteins involved in clathrin-mediated endocytosis, a process in which NECAP 2 plays a role. By influencing these phosphorylation states, these compounds could increase NECAP 2 activity.
On the other hand, Y-27632, Blebbistatin, Wiskostatin, Jasplakinolide, Latrunculin A, and Cytochalasin D modulateactin dynamics, which is closely tied to clathrin-mediated endocytosis. For instance, Y-27632 modulates actin dynamics. Similarly, Blebbistatin inhibits myosin II, Wiskostatin targets the neural Wiskott-Aldrich syndrome protein (N-WASP), Jasplakinolide stabilizes actin filaments, and both Latrunculin A and Cytochalasin D inhibit actin polymerization. By influencing actin dynamics, these compounds could indirectly enhance NECAP 2 activity through their effects on clathrin-mediated endocytosis.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Chloro-N6-cyclopentyladenosine | 37739-05-2 | sc-203460 sc-203460A | 10 mg 50 mg | $141.00 $599.00 | ||
CPA is an adenosine A1 receptor agonist. By activating this receptor, it can decrease cyclic AMP levels, which could indirectly stimulate NECAP 2 activity due to its involvement in clathrin-mediated endocytosis, a process modulated by cAMP. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a plant-derived compound known to activate adenylate cyclase, increasing cAMP production. As cAMP influences clathrin-mediated endocytosis, a process involving NECAP 2, this compound could indirectly enhance NECAP 2 activity. | ||||||
PKC-412 | 120685-11-2 | sc-200691 sc-200691A | 1 mg 5 mg | $52.00 $114.00 | 10 | |
PKC 412 is a protein kinase C inhibitor. By inhibiting PKC, it can influence the phosphorylation state of proteins involved in clathrin-mediated endocytosis, a process in which NECAP 2 plays a role, potentially increasing NECAP 2 activity. | ||||||
Calphostin C | 121263-19-2 | sc-3545 sc-3545A | 100 µg 1 mg | $343.00 $1642.00 | 20 | |
Calphostin C is a potent and selective inhibitor of protein kinase C. By influencing protein phosphorylation state, it could indirectly stimulate NECAP 2 activity through its impact on clathrin-mediated endocytosis. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a selective inhibitor of Rho-associated protein kinases (ROCKs). By inhibiting ROCKs, it can modulate actin dynamics, possibly influencing clathrin-mediated endocytosis, a process in which NECAP 2 is involved, and thus potentially enhancing NECAP 2 activity. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Blebbistatin is an inhibitor of myosin II. By inhibiting myosin II, it can modulate actin dynamics, potentially influencing clathrin-mediated endocytosis, a process involving NECAP 2, and indirectly enhancing NECAP 2 activity. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Wiskostatin is a selective inhibitor of the neural Wiskott-Aldrich syndrome protein (N-WASP). As N-WASP regulates actin polymerization, its inhibition could influence clathrin-mediated endocytosis and indirectly enhance NECAP 2 activity. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Jasplakinolide stabilizes actin filaments and promotes actin polymerization. This could indirectly stimulate NECAP 2 activity by influencing clathrin-mediated endocytosis, a process in which NECAP 2 is involved. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A is an actin polymerization inhibitor. By influencing actin dynamics, it could modulate clathrin-mediated endocytosis, a process involving NECAP 2, and indirectly enhance NECAP 2 activity. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D is an inhibitor of actin polymerization. It could indirectly enhance NECAP 2 activity by influencing clathrin-mediated endocytosis, a process in which NECAP 2 is involved. | ||||||