Myt 1 Activators
Myt1, also known as Membrane-associated tyrosine/threonine 1, is a crucial protein in the human body, encoded by the PKMYT1 gene. This protein functions primarily as a cell cycle regulator, specifically inhibiting cyclin-dependent kinases (CDKs). CDKs are instrumental in the progression of the cell cycle, and by inhibiting them, Myt1 plays a significant role in preventing premature entry into mitosis, particularly in the G2/M phase of the cell cycle. Myt1's regulatory function is essential for maintaining the balance and timing of cellular division and growth, thus ensuring the overall health and functionality of cells. Notably, the expression of this protein is regulated by the p53 tumor suppressor gene, although the precise mechanism of this regulation continues to be a subject of ongoing research.
The expression of Myt1 can be influenced by various chemical compounds, many of which are naturally occurring. For instance, retinoic acid, a derivative of vitamin A, could potentially induce the expression of Myt1 due to its role in promoting cellular differentiation and cell cycle arrest. Similarly, curcumin, a polyphenol found in turmeric, may stimulate the expression of Myt1 as part of its anti-proliferative effects on cells. Another example is resveratrol, a polyphenolic compound found in grapes, which might stimulate Myt1 expression by promoting cell cycle arrest. Other compounds, such as genistein, sulforaphane, and epigallocatechin gallate (EGCG), found respectively in soy, cruciferous vegetables, and green tea, could also potentially enhance the expression of Myt1 due to their roles in cell cycle regulation and apoptosis. However, these relationships are complex and multifaceted, and further research is needed to fully understand the molecular mechanisms underlying these effects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a vitamin A derivative, may induce Myt1 expression through its role in promoting differentiation and cell cycle arrest, potentially increasing the need for Myt1's CDK-inhibiting functions. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a polyphenol from turmeric that exhibits potential anti-proliferative effects on cells, possibly leading to upregulation of Myt1 as part of a response to suppress cell cycle progression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenolic compound found in grapes, might stimulate Myt1 expression by promoting cell cycle arrest, thus augmenting the need for Myt1's inhibitory role on CDKs. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid found in several fruits and vegetables, may potentially induce Myt1 expression by influencing cell cycle checkpoints, possibly enhancing the requirement for Myt1's regulation of CDKs. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a soy isoflavone, may enhance Myt1 expression through its influence on cell cycle regulation and apoptosis, potentially increasing the demand for Myt1's inhibitory role on CDKs. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
DL-Sulforaphane, a compound found in cruciferous vegetables, might promote Myt1 expression by influencing cell cycle arrest and apoptosis, possibly enhancing the need for Myt1's inhibition of CDKs. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
(-)-Epigallocatechin Gallate, a major catechin in green tea, could upregulate Myt1 expression as part of its role in cell cycle regulation and apoptosis, potentially increasing the demand for Myt1's CDK-inhibiting functions. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $39.00 $61.00 $146.00 $312.00 $1032.00 | 5 | |
Indole-3-carbinol, found in cruciferous vegetables, may stimulate Myt1 expression by influencing cell cycle regulation, potentially augmenting the need for Myt1's inhibitory role on CDKs. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $146.00 $582.00 $6248.00 | 4 | |
Lycopene, a carotenoid found in tomatoes, may induce Myt1 expression through its potential cell cycle arresting and anti-proliferative effects, possibly increasing the requirement for Myt1's CDK-inhibiting functions. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid, a polyphenol found in berries and pomegranates, could potentially upregulate Myt1 expression due to its role in cell cycle regulation, potentially enhancing the need for Myt1's inhibitory role on CDKs. | ||||||