Mucin 20 inhibitors work by affecting specific biochemical or cellular pathways where Mucin 20 is involved. These inhibitors target phosphorylation events and signaling pathways that Mucin 20 partakes in, thereby reducing its functional activity. Staurosporine, Genistein, PP2, and SU6656 are kinase inhibitors that can alter Mucin 20's function by influencing the phosphorylation state or impacting signaling pathways related to signal transduction. LY294002 and Wortmannin, as PI3K inhibitors, can affect the functional activity of Mucin 20 by inhibiting PI3K-associated signaling pathways. U73122 is a phospholipase C inhibitor that can affect the functional activity of Mucin 20 by inhibiting phospholipase C-associated signal transduction processes.
Y-27632, a ROCK inhibitor, influences the functional activity of Mucin 20, which is part of these pathways. PD98059 is an ERK inhibitor that can affect the functional activity of Mucin 20 by inhibiting the ERK pathway, while SP600125, a JNK inhibitor, and SB203580, a p38 MAP kinase inhibitor, function by inhibitingtheir respective pathways where Mucin 20 is involved. Lastly, BAPTA-AM acts as a calcium chelator, which can lead to a decrease in Mucin 20's functional activity by inhibiting calcium-dependent signal transduction pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor. Mucin 20 is a membrane-associated protein, and its function can be influenced by the phosphorylation state. Staurosporine can inhibit the function of Mucin 20 by modifying its phosphorylation state. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein is a tyrosine kinase inhibitor. It can inhibit the phosphorylation of proteins involved in various signaling pathways. As Mucin 20 is involved in signal transduction, the inhibition of tyrosine kinases can affect the functional activity of Mucin 20. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor. PI3K is involved in several signaling pathways, and its inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor. The inhibition of PI3K can lead to a reduction in the functional activity of Mucin 20, which is involved in PI3K-associated signaling pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a ROCK inhibitor. Rho-associated coiled-coil forming kinase (ROCK) is involved in various signaling pathways, and its inhibition can influence the functional activity of Mucin 20, which is part of these pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is an ERK inhibitor. The ERK pathway is involved in various cellular processes, and its inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. JNK pathways are involved in various cellular processes, and its inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAP kinase inhibitor. The p38 MAP kinase is involved in various signaling pathways, and its inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is an Src family tyrosine kinase inhibitor. The Src family kinases are involved in various signaling pathways, and their inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||
SU6656 | 330161-87-0 | sc-203286 sc-203286A | 1 mg 5 mg | $56.00 $130.00 | 27 | |
SU6656 is a selective Src family kinase inhibitor. The Src family kinases are involved in various signaling pathways, and their inhibition can affect the functional activity of proteins involved in these pathways, including Mucin 20. | ||||||