Mucin 13 Inhibitors
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $152.00 $214.00 $728.00 $2601.00 $10965.00 $21838.00 $41096.00 | 5 | |
Suramin, a polysulfonated naphthylurea, inhibits Mucin 13 indirectly by disrupting the purinergic signaling pathway. It antagonizes P2 receptors involved in purinergic signaling, affecting downstream events related to mucin expression and secretion. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Tunicamycin, an antibiotic, indirectly modulates Mucin 13 by inhibiting N-linked glycosylation. As an inhibitor of oligosaccharyltransferase, it disrupts the synthesis of N-linked glycoproteins, including mucins. The inhibition of N-linked glycosylation by tunicamycin alters the post-translational modification of Mucin 13, influencing its cellular localization and function. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Brefeldin A, a fungal metabolite, indirectly inhibits Mucin 13 by disrupting the Golgi apparatus and vesicular transport. It inhibits ADP-ribosylation factor (ARF), leading to the disassembly of the Golgi complex and inhibition of vesicle formation. The disruption of vesicular transport by brefeldin A affects the trafficking of mucins, including Mucin 13, altering their secretion and localization. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a fungal metabolite and PI3-kinase inhibitor, indirectly influences Mucin 13 by disrupting the phosphoinositide 3-kinase (PI3K) pathway. PI3K is involved in cellular processes, including mucin regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, a macrolide antibiotic, indirectly modulates Mucin 13 by inhibiting the mammalian target of rapamycin (mTOR) pathway. As an mTOR inhibitor, rapamycin disrupts the signaling cascade involved in mucin regulation. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
2-Deoxy-D-glucose, a glucose analog, indirectly influences Mucin 13 by disrupting glycolysis. As a competitive inhibitor of glucose, it interferes with the glycolytic pathway, impacting cellular energy metabolism. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $31.00 $128.00 $454.00 | 45 | |
SB-202190, a selective inhibitor of p38 mitogen-activated protein kinase (MAPK), indirectly influences Mucin 13 by disrupting the MAPK pathway. p38 MAPK is implicated in cellular stress responses, and its inhibition by SB-202190 affects downstream targets. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
Geldanamycin, an ansamycin antibiotic, indirectly inhibits Mucin 13 by targeting heat shock protein 90 (Hsp90). It binds to Hsp90, leading to the degradation of client proteins involved in mucin regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, a phosphoinositide 3-kinase (PI3K) inhibitor, indirectly influences Mucin 13 by disrupting the PI3K pathway. PI3K is implicated in cellular processes, including mucin regulation. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a selective inhibitor of mitogen-activated protein kinase kinase (MEK), indirectly modulates Mucin 13 by disrupting the MAPK pathway. MEK is a critical component of the MAPK cascade, which plays a role in mucin regulation. | ||||||