Date published: 2025-12-12

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Msx-2 Inhibitors

Msx-2 inhibitors constitute a distinct chemical class of compounds that specifically target the transcription factor known as Msx-2 (Msh homeobox 2). Msx-2 is a key regulatory protein involved in various developmental processes, including skeletal development, craniofacial morphogenesis, and tooth formation. The inhibitors belonging to this class are designed to interact with Msx-2 at a molecular level, aiming to modulate its activity or expression. Through precise molecular interactions, these inhibitors work to interfere with the normal functions of Msx-2, which plays a critical role in controlling gene expression patterns during embryonic development and tissue differentiation.

As Msx-2 is involved in multiple pathways and cellular processes, the design and development of these inhibitors require careful consideration of their specific binding sites and their potential effects on downstream cellular events. Researchers continue to explore and investigate the properties and mechanisms of Msx-2 inhibitors, aiming to uncover their full range of effects and potential applications in biological research and beyond.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ro 31-8220

138489-18-6sc-200619
sc-200619A
1 mg
5 mg
$90.00
$240.00
17
(1)

This compound is a kinase inhibitor that has demonstrated inhibitory effects on MSX-2 expression in certain studies.

Chelerythrine chloride

3895-92-9sc-3547
sc-3547A
5 mg
25 mg
$88.00
$311.00
17
(1)

A benzophenanthridine alkaloid that has exhibited inhibitory effects on MSX-2 expression in certain experimental setups.

Ursolic Acid

77-52-1sc-200383
sc-200383A
50 mg
250 mg
$55.00
$176.00
8
(1)

A natural triterpenoid found in various plants that has shown to downregulate MSX-2 expression in specific contexts.

Niclosamide

50-65-7sc-250564
sc-250564A
sc-250564B
sc-250564C
sc-250564D
sc-250564E
100 mg
1 g
10 g
100 g
1 kg
5 kg
$37.00
$77.00
$184.00
$510.00
$1224.00
$5814.00
8
(1)

Known as an anthelmintic drug, niclosamide has been identified as a potential MSX-2 inhibitor.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

A derivative of vitamin A, retinoic acid has demonstrated inhibitory effects on MSX-2 expression during certain stages of development.

BMS-345541

445430-58-0sc-221741
1 mg
$306.00
1
(1)

A selective inhibitor of the IκB kinase (IKK) that has been reported to inhibit MSX-2 expression in some studies.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

A potent histone deacetylase (HDAC) inhibitor that has been shown to modulate MSX-2 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

A bioactive compound found in turmeric, curcumin has exhibited inhibitory effects on MSX-2 expression in certain experimental models.