Msx-2 inhibitors constitute a distinct chemical class of compounds that specifically target the transcription factor known as Msx-2 (Msh homeobox 2). Msx-2 is a key regulatory protein involved in various developmental processes, including skeletal development, craniofacial morphogenesis, and tooth formation. The inhibitors belonging to this class are designed to interact with Msx-2 at a molecular level, aiming to modulate its activity or expression. Through precise molecular interactions, these inhibitors work to interfere with the normal functions of Msx-2, which plays a critical role in controlling gene expression patterns during embryonic development and tissue differentiation.
As Msx-2 is involved in multiple pathways and cellular processes, the design and development of these inhibitors require careful consideration of their specific binding sites and their potential effects on downstream cellular events. Researchers continue to explore and investigate the properties and mechanisms of Msx-2 inhibitors, aiming to uncover their full range of effects and potential applications in biological research and beyond.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ro 31-8220 | 138489-18-6 | sc-200619 sc-200619A | 1 mg 5 mg | $90.00 $240.00 | 17 | |
This compound is a kinase inhibitor that has demonstrated inhibitory effects on MSX-2 expression in certain studies. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
A benzophenanthridine alkaloid that has exhibited inhibitory effects on MSX-2 expression in certain experimental setups. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $55.00 $176.00 | 8 | |
A natural triterpenoid found in various plants that has shown to downregulate MSX-2 expression in specific contexts. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $37.00 $77.00 $184.00 $510.00 $1224.00 $5814.00 | 8 | |
Known as an anthelmintic drug, niclosamide has been identified as a potential MSX-2 inhibitor. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A derivative of vitamin A, retinoic acid has demonstrated inhibitory effects on MSX-2 expression during certain stages of development. | ||||||
BMS-345541 | 445430-58-0 | sc-221741 | 1 mg | $306.00 | 1 | |
A selective inhibitor of the IκB kinase (IKK) that has been reported to inhibit MSX-2 expression in some studies. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A potent histone deacetylase (HDAC) inhibitor that has been shown to modulate MSX-2 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A bioactive compound found in turmeric, curcumin has exhibited inhibitory effects on MSX-2 expression in certain experimental models. | ||||||