MRP-L55 activators encompass a distinct group of chemical entities designed to enhance the activity of the MRP-L55 protein, which plays a crucial role in cellular mechanisms. The development of these activators is rooted in a deep understanding of the protein's structure and the biochemical pathways it influences. Scientists employ state-of-the-art techniques in molecular biology and chemistry to identify and optimize molecules capable of interacting with MRP-L55 in a manner that increases its functional activity. This involves the use of computational modeling to predict how different chemical structures will interact with the protein, focusing on those regions of the protein that are amenable to activation by small molecules. Through iterative processes of synthesis and modification, researchers aim to improve the binding efficiency and specificity of these activators to MRP-L55, using a variety of chemical frameworks as potential starting points.
Experimental validation plays a pivotal role in the development of MRP-L55 activators. Techniques such as X-ray crystallography and NMR spectroscopy are employed to elucidate the three-dimensional structure of the protein in complex with the activators, providing insights into the molecular interactions that underlie activation. Biochemical assays are then used to measure the increase in MRP-L55 activity in the presence of these compounds, enabling the assessment of their efficacy. Through a combination of computational design, chemical synthesis, and rigorous biological testing, the field aims to develop molecules that can reliably increase the activity of MRP-L55, thereby influencing the protein's role in cellular processes.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
Mimics energy depletion, potentially upregulating MRPL55 in response to increased ATP demand. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Influences gene expression; could induce MRPL55 as part of mitochondrial biogenesis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates SIRT1, which may lead to the induction of MRPL55 as part of enhanced mitochondrial function. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $118.00 $320.00 $622.00 $928.00 $1234.00 | 38 | |
May upregulate MRPL55 expression by promoting mitochondrial biogenesis. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
A precursor of NAD+, could enhance MRPL55 expression by supporting mitochondrial functions and energy metabolism. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
As a PPAR agonist, might induce MRPL55 to support mitochondrial proliferation and function. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Another PPARγ agonist, could upregulate MRPL55 as part of a cellular strategy to enhance mitochondrial capacity. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
An amino acid known to stimulate mTOR, potentially enhancing MRPL55 expression as part of mitochondrial protein synthesis. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Known to induce autophagy, which can lead to mitochondrial renewal and possibly the upregulation of MRPL55. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
May influence pathways of mitochondrial biogenesis, leading to increased MRPL55 expression. | ||||||