Date published: 2026-5-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

MRP-L23 Inhibitors

Large ribosomal subunit protein uL23m Inhibitors would primarily encompass molecules that have an affinity for disrupting the expression or function of this specific ribosomal protein. Given the protein's assumed role in the large ribosomal subunit, inhibitors might act through different mechanisms. Some could hinder the transcription of the uL23m gene by directly interfering with the RNA polymerase machinery, as seen with compounds like α-Amanitin or Rifampicin. Others, like 5-Fluorouracil, might incorporate into nascent RNA and disrupt normal RNA synthesis and maturation processes. Another subset of inhibitors might work post-transcriptionally, perhaps by hindering the proper assembly of the ribosome or preventing the incorporation of the uL23m protein into the larger ribosomal complex. Tetracycline and Chloramphenicol, for instance, have a known affinity for ribosomes and might alter the ribosome's structure in a way that impacts the uL23m protein. In essence, the specificity, mechanism, and efficacy of these inhibitors would depend on their chemical structure and the exact nature of their interactions with ribosomal components.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin D binds to the DNA double helix, inhibiting RNA synthesis and potentially the expression of Large ribosomal subunit protein uL23m.

Rifampicin

13292-46-1sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$97.00
$328.00
$676.00
$1467.00
6
(1)

Rifampicin can bind to RNA polymerase, potentially leading to the decreased transcription of genes, including those for ribosomal proteins.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$69.00
$266.00
8
(1)

Mycophenolic acid is an inhibitor of inosine monophosphate dehydrogenase, which can affect RNA synthesis, potentially reducing the expression of ribosomal proteins.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

α-Amanitin binds and inhibits RNA polymerase II, which could suppress the transcription of ribosomal protein genes.

Fluorouracil

51-21-8sc-29060
sc-29060A
1 g
5 g
$37.00
$152.00
11
(1)

5-Fluorouracil gets incorporated into RNA, potentially leading to disrupted RNA synthesis and reduced expression of ribosomal proteins.

Tetracycline

60-54-8sc-205858
sc-205858A
sc-205858B
sc-205858C
sc-205858D
10 g
25 g
100 g
500 g
1 kg
$63.00
$94.00
$270.00
$417.00
$634.00
6
(1)

Tetracycline can bind to the small ribosomal subunit, but its binding might also impact the overall ribosome function and related protein expression.

Chloramphenicol

56-75-7sc-3594
25 g
$90.00
10
(1)

Chloramphenicol binds to the large ribosomal subunit, potentially affecting the synthesis or expression of associated proteins.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$58.00
$186.00
$94.00
21
(2)

Camptothecin inhibits DNA topoisomerase I, which can lead to a disruption in DNA replication and potentially RNA synthesis, affecting ribosomal protein expression.

Novobiocin

303-81-1sc-362034
sc-362034A
5 mg
25 mg
$128.00
$380.00
(0)

Novobiocin targets DNA gyrase, and its inhibition can impact DNA processes that might indirectly influence the expression of ribosomal proteins.