Molecular structure of Tetracycline, CAS Number: 60-54-8
Tetracycline (CAS 60-54-8)
See product citations (6)
Alternate Names:
Deschlorobiomycin; Ambramycin; Liquamycin
Application:
Tetracycline is a compound that has been shown to induce apoptosis in various cells
CAS Number:
60-54-8
Molecular Weight:
444.43
Molecular Formula:
C22H24N2O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Tetracycline is employed in microbiological research to study bacterial behavior and genetics, as it serves as a selective agent in various culture media. Due to its broad-spectrum antibiotic properties, tetracycline is used in the development of recombinant DNA by allowing only the growth of bacteria that have been successfully transformed with tetracycline-resistance genes. In molecular biology, this chemical is used as a tool to control gene expression in a system known as the Tet-on and Tet-off gene expression system, which allows for the regulation of gene activity in experimental applications. Tetracycline is also involved in research to understand the mechanisms of antibiotic resistance, providing insights into how bacteria evade the effects of antibiotics. Moreover, it is a standard reagent in the study of bacterial protein synthesis, as it binds to the 30S subunit of bacterial ribosomes, inhibiting the addition of amino acids to the elongating peptide chain.
Tetracycline (CAS 60-54-8) References
- Tetracycline sensing using novel doxycycline derivatives immobilized on different surface plasmon resonance biosensor surfaces. | Andree, U., et al. 2010. Bioanalysis. 2: 217-27. PMID: 21083305
- Abiotic transformation products of tetracycline and chlortetracycline in salt solutions and manure. | Keßler, DN., et al. 2019. Chemosphere. 224: 487-493. PMID: 30831500
- Toxicity of tetracycline and its transformation products to a phosphorus removing Shewanella strain. | Long, S., et al. 2020. Chemosphere. 246: 125681. PMID: 31896014
- Whole-cell paper strip biosensors to semi-quantify tetracycline antibiotics in environmental matrices. | Ma, Z., et al. 2020. Biosens Bioelectron. 168: 112528. PMID: 32890930
- Construction of S-scheme 1D/2D rod-like g-C3N4/V2O5 heterostructure with enhanced sonophotocatalytic degradation for Tetracycline antibiotics. | Preeyanghaa, M., et al. 2022. Chemosphere. 287: 132380. PMID: 34600002
- Time-course evolution of bacterial community tolerance to tetracycline antibiotics in agricultural soils: A laboratory experiment. | Santás-Miguel, V., et al. 2022. Chemosphere. 291: 132758. PMID: 34736938
- Hydrolytic transformation mechanism of tetracycline antibiotics: Reaction kinetics, products identification and determination in WWTPs. | Zhong, SF., et al. 2022. Ecotoxicol Environ Saf. 229: 113063. PMID: 34890985
- N self-doped hierarchically porous carbon derived from biomass as an efficient adsorbent for the removal of tetracycline antibiotics. | Wang, T., et al. 2022. Sci Total Environ. 822: 153567. PMID: 35114240
- Tetracycline degradation by nonthermal plasma: removal efficiency, degradation pathway, and toxicity evaluation. | Ouzar, A. and Kim, IK. 2022. Water Sci Technol. 86: 2794-2807. PMID: 36515189
- [Co-occurrence of Tetracycline Antibiotic Resistance Genes and Microbial Communities in Plateau Wetlands Under the Influence of Human Activities]. | Qin, R., et al. 2023. Huan Jing Ke Xue. 44: 169-179. PMID: 36635805
- Structure-Based Design of Bisubstrate Tetracycline Destructase Inhibitors That Block Flavin Redox Cycling. | Williford, EE., et al. 2023. J Med Chem. 66: 3917-3933. PMID: 36877173
- An aptamer array for discriminating tetracycline antibiotics based on binding-enhanced intrinsic fluorescence. | Zhao, Y., et al. 2023. Analyst. 148: 1507-1513. PMID: 36891736
- Tetracycline pleurodesis during active pulmonary-pleural air leak for prevention of recurrent pneumothorax. | Macoviak, JA., et al. 1982. Chest. 81: 78-81. PMID: 7053946
Inhibitor of:
α-defensin 1B, β-defensin 108B, β-defensin 118, β-defensin 124, β-defensin 125, β-defensin 4, β-defensin 5, 2610528E23Rik, 2900024O10Rik, AARS2, ACY1L2, ADAMTS-9, Ajuba, AlaRS, ALB, amelotin, ATP5L2, ATP6, BOLA3, Brucella abortus, Brucella abortus LPS, C. trachomatis MOMP, C12orf65_2810006K23Rik, C14orf149, C19orf12, C3orf26, C3orf60, C7orf44, CCDC44, CEMP1, Ces3b, Chlamydia LPS, CNF2, COA1, COL17A1, Collagen α1, COX20, CRABP-II, CRBP II, CRS1C-2, CRS4C-5, cryptdin 22, cryptdin 3, Csprs, CysRS, Ddc8, DDX3L, Diphtheria Toxin, DMP-1, Dynein IC2, E. coli, Edwardsiella tarda, EF-1 ε1, EF-1 γ, EF-1β, EF-G1, EF-G2, EF-Ts, EG665562, elastin, EMID1, Enamelin, Enrofloxacin, Epilysin, ERAL1, eRF3a, eRF3b, Erwinia herbicola, exonucleasefamily surface anchored protein, Extracellular solute-binding protein, Francisella tularensis LPS, GluRS, GTPBP1, GTPBP10, GTPBP5, H. influenzae B, HARS2, Histatin 2, HSP 65, HTPAP, IAP, IARS2, ICT1, IF2, IL-8RA, IleRS, IMMP2L, INOC1, JTV1, LARS2, LeuRS, Liprin α4, LMLN, LOC645485, LONP2, LPAAT-θ, LRP, MARS2, Metaxin 3, METH-1, MINOS1, MIPEP, mitochondrial ferritin, Mitoferrin, MMP-13, MMP-1b, MRP-63, MRP-L1, MRP-L19, MRP-L20, MRP-L33, MRP-L46, MRP-L47, MRP-L54, MRP-S22, MRPL28, MTFmt, Mtif3, MTMR12, NELL1, NIMP, Ob, OR8J1, Osteoglycin, OTTMUSG00000008561, Phosphotransacetylase, Procollagen Type I, PrP, PTCD2, PYROXD2, QCR10, QRSL1, RARS2, RECK, Rhodopsin, Ribosomal Protein L10L, Ribosomal Protein L19, Ribosomal Protein L24, Ribosomal Protein L27a, Ribosomal Protein L28, Ribosomal Protein L29, Ribosomal Protein L36aL, Ribosomal Protein L38, Ribosomal Protein L39, Ribosomal Protein L5, Ribosomal Protein L9, Ribosomal Protein LP1, Ribosomal Protein S10, Ribosomal Protein S12, Ribosomal Protein S13, Ribosomal Protein S14, Ribosomal Protein S15a, Ribosomal Protein S16, Ribosomal Protein S2, Ribosomal Protein S20, Ribosomal Protein S21, Ribosomal Protein S24, Ribosomal Protein S28, Ribosomal Protein S3, Ribosomal Protein S5, Ribosomal Protein S9, Ribosome (RPL; 40S; 60S), RMND1, RPL10L, RPL24, RPL26L1, RPL39, RPL39L, RPS2, RPS4Y1, RPS4Y2, RPS4YX, RPUSD4, rRNA, S19BP, Salmonella (Enterobacterales), Salmonella paratyphi 0-2, Salmonella typhimurium 0-4, Shigatoxin 2, Shigella dysenteriae, Sigma 54, SRp40, Streptococcus agalactiae, Sup35, TaR, TaR-1, TARSL1, TCP-1 ζ, Telethonin, Tenascin-R, TIMP-4, TINP1, TOE1, Twinkle, UQCRB, UQCRC2, VacA, VARS2, WARS2, YFP, and ZnT-7.Activator of:
ABCF2, Bicoid, ClpP, Cre Recombinase, DaRS, DsRed2, EBFP, EF-Tu, Eme2, Enterobacter cloacae, GAL4 (DBD), GFP, H. influenzae B, IF3, INSC, L-Myc, Laminin α-3, LOC100039786, LOC100041076, LOC100041351, MBNL3, MMP-10, MMP-19, MMP-1b, MOMP, MRP-L30, MT-MMP-6, Mycoplasma hominis p120, NOTO, OR2AK2, OR2G2, PA, PBP, pelota, ProRS, PTCD3, QM, RFLAT-1, RFRP, RGPD, Ribosomal Protein L12, Ribosomal Protein L22, Ribosomal Protein L23, Ribosomal Protein L32, Ribosomal Protein L36a, Ribosomal Protein S21, Ribosomal Protein S26, SerRS, Ste3, Streptococcus Group B, THUMPD1, TIMP-2, VLP, YANK2, YBEY, and Yfh1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tetracycline, 10 g | sc-205858 | 10 g | $63.00 | |||
Tetracycline, 25 g | sc-205858A | 25 g | $94.00 | |||
Tetracycline, 100 g | sc-205858B | 100 g | $270.00 | |||
Tetracycline, 500 g | sc-205858C | 500 g | $417.00 | |||
Tetracycline, 1 kg | sc-205858D | 1 kg | $634.00 |