Date published: 2025-10-26

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MPZL1 Inhibitors

MPZL1 inhibitors represent a class of chemical compounds that have gained prominence in the field of cellular biology and signal transduction research. These inhibitors are specifically designed to target and modulate the activity of MPZL1, also known as myelin protein zero-like 1. MPZL1 is a transmembrane protein primarily found on the surface of various cell types, including immune cells and cancer cells. It has been associated with a wide range of cellular processes, such as cell adhesion, migration, and receptor signaling. MPZL1 is notable for its involvement in immune cell activation, particularly in T cells, where it plays a role in regulating T cell receptor signaling and cellular responses.

MPZL1 inhibitors exert their effects by interfering with the function or expression of MPZL1, disrupting its role in cell adhesion, migration, and signaling events. This interference can have far-reaching consequences for cellular behaviors and responses, particularly within the context of immune cell activation and tumor cell behavior. Researchers utilize MPZL1 inhibitors as invaluable tools to investigate the specific roles of MPZL1 in different cellular contexts and to better understand the molecular mechanisms underlying cell signaling and immune cell activation. While the precise applications and broader implications of MPZL1 inhibitors are subjects of ongoing research, their utility in unraveling the complexities of cellular biology, especially in relation to immune responses and cancer biology, is of paramount importance in advancing our understanding of signal transduction and cell function.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Interferes with DNA-dependent RNA synthesis by binding to DNA, which might decrease MPZL1 mRNA transcription.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Inhibits eukaryotic protein synthesis by interfering with the translocation step, which could reduce MPZL1 protein levels.

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Acts as a DNA crosslinker that can lead to inhibition of DNA synthesis and thus potentially downregulate MPZL1 gene expression.

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

A diterpene triepoxide that may inhibit transcriptional activity, potentially affecting MPZL1 protein expression.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$56.00
$260.00
$980.00
163
(3)

Proteasome inhibitor that can lead to reduced degradation of regulatory proteins, potentially influencing MPZL1 expression.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Inhibits DNA topoisomerase I, leading to DNA damage and possibly the downregulation of certain genes including MPZL1.

Chloroquine

54-05-7sc-507304
250 mg
$68.00
2
(0)

Known to inhibit lysosomal activity and autophagy, which could impact protein turnover and expression including MPZL1.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, which may reduce MPZL1 gene expression.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Binds to GC-rich sequences in DNA, potentially inhibiting transcription factors and decreasing MPZL1 expression.

Puromycin

53-79-2sc-205821
sc-205821A
10 mg
25 mg
$163.00
$316.00
436
(1)

Causes premature chain termination during protein synthesis, which could indirectly reduce the levels of MPZL1.