MPZL1 inhibitors represent a class of chemical compounds that have gained prominence in the field of cellular biology and signal transduction research. These inhibitors are specifically designed to target and modulate the activity of MPZL1, also known as myelin protein zero-like 1. MPZL1 is a transmembrane protein primarily found on the surface of various cell types, including immune cells and cancer cells. It has been associated with a wide range of cellular processes, such as cell adhesion, migration, and receptor signaling. MPZL1 is notable for its involvement in immune cell activation, particularly in T cells, where it plays a role in regulating T cell receptor signaling and cellular responses.
MPZL1 inhibitors exert their effects by interfering with the function or expression of MPZL1, disrupting its role in cell adhesion, migration, and signaling events. This interference can have far-reaching consequences for cellular behaviors and responses, particularly within the context of immune cell activation and tumor cell behavior. Researchers utilize MPZL1 inhibitors as invaluable tools to investigate the specific roles of MPZL1 in different cellular contexts and to better understand the molecular mechanisms underlying cell signaling and immune cell activation. While the precise applications and broader implications of MPZL1 inhibitors are subjects of ongoing research, their utility in unraveling the complexities of cellular biology, especially in relation to immune responses and cancer biology, is of paramount importance in advancing our understanding of signal transduction and cell function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Interferes with DNA-dependent RNA synthesis by binding to DNA, which might decrease MPZL1 mRNA transcription. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with the translocation step, which could reduce MPZL1 protein levels. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Acts as a DNA crosslinker that can lead to inhibition of DNA synthesis and thus potentially downregulate MPZL1 gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
A diterpene triepoxide that may inhibit transcriptional activity, potentially affecting MPZL1 protein expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor that can lead to reduced degradation of regulatory proteins, potentially influencing MPZL1 expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, leading to DNA damage and possibly the downregulation of certain genes including MPZL1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Known to inhibit lysosomal activity and autophagy, which could impact protein turnover and expression including MPZL1. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, which may reduce MPZL1 gene expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to GC-rich sequences in DNA, potentially inhibiting transcription factors and decreasing MPZL1 expression. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $163.00 $316.00 | 436 | |
Causes premature chain termination during protein synthesis, which could indirectly reduce the levels of MPZL1. | ||||||