MORF4L2 Activators
MORF4L2 activators are a class of chemical compounds that exert their biological effects by modulating the activity of the MORF4L2 protein. MORF4L2, also known as Mortality Factor 4-Like 2, is a nuclear protein that plays a critical role in chromatin remodeling and gene regulation. These activators are designed to enhance the function of MORF4L2, thereby influencing various cellular processes that are mediated by this protein.
MORF4L2 is a component of the nucleosome remodeling and histone deacetylase (NuRD) complex, which is involved in regulating chromatin structure and gene expression. By activating MORF4L2, these chemical compounds can potentially enhance the efficiency of chromatin remodeling and gene transcription processes. This can lead to a cascade of downstream effects on cellular function, as gene expression is fundamental to the regulation of various biological processes. MORF4L2 activators can be valuable tools for researchers in elucidating the intricacies of gene regulation, as they allow for precise control over the activity of this key protein. Moreover, understanding the mechanisms by which MORF4L2 activators influence gene expression can have broad implications in fields such as molecular biology, genetics, and epigenetics, contributing to the advancement of our knowledge about how genes are turned on or off in different cellular contexts. This class of chemicals has the potential to shed light on the intricate workings of gene regulation and chromatin structure, offering insights into fundamental cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
by enhancing histone acetyltransferase (HAT) activity, which, in turn, increases gene regulation and chromatin structure. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Indirectly activates MORF4L2 as an inhibitor of the PI3K/Akt pathway, by affecting downstream signaling, potentially increasing gene expression and chromatin remodeling processes. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Indirectly increases MORF4L2 activity as a bromodomain inhibitor, disrupting the recognition of acetylated histones and thereby increasing MORF4L2's interaction with chromatin. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Indirectly increases MORF4L2 activity as a PARP inhibitor, by affecting DNA repair processes, which can subsequently influence chromatin remodeling and gene regulation. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Indirectly increases MORF4L2 by impacting transcription and gene expression with this RNA polymerase inhibitor, thus affecting MORF4L2-mediated chromatin remodeling. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Indirectly activates MORF4L2 as an inhibitor of topoisomerases involved in DNA relaxation and transcription, which can lead to changes in chromatin structure and gene expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
Indirectly activates MORF4L2 by potentially altering histone phosphorylation and transcription with this CDK inhibitor, influencing chromatin structure and gene regulation. | ||||||