Monocyte to macrophage differentiation-associated (MMD) is a protein encoded by the MMD gene in humans. This protein is named for its role in the differentiation process of monocytes into macrophages, which is a critical step in the immune response.Monocytes are a type of white blood cell that can differentiate into macrophages or dendritic cells depending on the signals they receive from their environment. Macrophages are crucial components of the immune system, involved in phagocytosis (ingestion of foreign particles), antigen presentation, and the release of cytokines that regulate other immune cells.
In terms of disease implications, any disruption in the monocyte to macrophage differentiation process could affect the immune response, making an individual more susceptible to infections or contributing to an overactive or dysregulated immune response. For example, an overactive macrophage response is implicated in certain inflammatory and auto-immune diseases.Furthermore, some studies suggest a role of MMD in atherosclerosis, a condition characterized by the build-up of fats, cholesterol, and other substances in and on artery walls.To summarize, MMD is a protein encoded by the MMD gene, involved in the differentiation of monocytes into macrophages. This role is vital for the immune response, and any disruptions could have implications for immune-related diseases and conditions like atherosclerosis.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 modulates immune responses and could influence monocyte to macrophage differentiation, potentially affecting MMD. | ||||||
GM-CSF | 83869-56-1 | sc-280759 | 5 µg | $516.00 | 1 | |
GM-CSF is crucial for macrophage differentiation and might indirectly impact MMD activity. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS activates macrophages and could indirectly affect MMD activity during immune responses. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has anti-inflammatory properties and might modulate macrophage function, potentially impacting MMD. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol modulates several immune pathways and could indirectly affect MMD in macrophage differentiation. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone, a PPARγ agonist, influences macrophage polarization and might affect MMD function. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a corticosteroid, can modulate immune responses and potentially impact MMD activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
All-trans Retinoic Acid affects immune cell differentiation and might impact MMD activity in macrophages. | ||||||
Sulfasalazine | 599-79-1 | sc-204312 sc-204312A sc-204312B sc-204312C | 1 g 2.5 g 5 g 10 g | $60.00 $75.00 $125.00 $205.00 | 8 | |
Sulfasalazine modulates inflammatory responses and may indirectly affect MMD during macrophage differentiation. | ||||||