Date published: 2025-12-19

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MMD Activators

Monocyte to macrophage differentiation-associated (MMD) is a protein encoded by the MMD gene in humans. This protein is named for its role in the differentiation process of monocytes into macrophages, which is a critical step in the immune response.Monocytes are a type of white blood cell that can differentiate into macrophages or dendritic cells depending on the signals they receive from their environment. Macrophages are crucial components of the immune system, involved in phagocytosis (ingestion of foreign particles), antigen presentation, and the release of cytokines that regulate other immune cells.

In terms of disease implications, any disruption in the monocyte to macrophage differentiation process could affect the immune response, making an individual more susceptible to infections or contributing to an overactive or dysregulated immune response. For example, an overactive macrophage response is implicated in certain inflammatory and auto-immune diseases.Furthermore, some studies suggest a role of MMD in atherosclerosis, a condition characterized by the build-up of fats, cholesterol, and other substances in and on artery walls.To summarize, MMD is a protein encoded by the MMD gene, involved in the differentiation of monocytes into macrophages. This role is vital for the immune response, and any disruptions could have implications for immune-related diseases and conditions like atherosclerosis.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D3 modulates immune responses and could influence monocyte to macrophage differentiation, potentially affecting MMD.

GM-CSF

83869-56-1sc-280759
5 µg
$516.00
1
(0)

GM-CSF is crucial for macrophage differentiation and might indirectly impact MMD activity.

Lipopolysaccharide, E. coli O55:B5

93572-42-0sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$96.00
$166.00
$459.00
$1615.00
12
(2)

LPS activates macrophages and could indirectly affect MMD activity during immune responses.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin has anti-inflammatory properties and might modulate macrophage function, potentially impacting MMD.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol modulates several immune pathways and could indirectly affect MMD in macrophage differentiation.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$54.00
$123.00
13
(1)

Pioglitazone, a PPARγ agonist, influences macrophage polarization and might affect MMD function.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$76.00
$82.00
$367.00
36
(1)

Dexamethasone, a corticosteroid, can modulate immune responses and potentially impact MMD activity.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

All-trans Retinoic Acid affects immune cell differentiation and might impact MMD activity in macrophages.

Sulfasalazine

599-79-1sc-204312
sc-204312A
sc-204312B
sc-204312C
1 g
2.5 g
5 g
10 g
$60.00
$75.00
$125.00
$205.00
8
(1)

Sulfasalazine modulates inflammatory responses and may indirectly affect MMD during macrophage differentiation.