The chemical class of MIP-3β Activators includes a range of compounds that could potentially influence the activity of MIP-3β (CCL19) indirectly. MIP-3β/CCL19 is a critical chemokine in the regulation of immune cell trafficking and plays a significant role in mediating inflammatory responses. The modulation of MIP-3β/CCL19 is closely linked to the immune system's response to inflammatory stimuli and various cellular signaling pathways.
Compounds such as Lipopolysaccharide (LPS) demonstrate their potential to modulate MIP-3β/CCL19 activity through their roles in inducing inflammatory responses. LPS, as a bacterial endotoxin,. Additionally, signaling molecules like Forskolin and Phorbol 12-myristate 13-acetate (PMA), which modulate cAMP levels and activate protein kinase C, respectively, highlight the complex interplay between cellular signaling and the regulation of chemokines like MIP-3β/CCL19.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
A bacterial endotoxin, could induce an inflammatory response potentially upregulating MIP-3β/CCL19. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Increases cAMP levels, might influence MIP-3β/CCL19 through cAMP-dependent signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C (PKC), potentially affecting MIP-3β/CCL19 through PKC-mediated signaling. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates various signaling pathways, could potentially influence MIP-3β/CCL19 expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid, can modulate inflammatory responses, potentially influencing MIP-3β/CCL19. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
Inhibits NF-κB, a key regulator of inflammatory gene expression, potentially affecting MIP-3β/CCL19. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $41.00 | 4 | |
An NSAID, could indirectly influence MIP-3β/CCL19 through its anti-inflammatory effects. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Affects various signaling pathways including those involved in inflammation, potentially modulating MIP-3β/CCL19. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Influences gene expression and cellular signaling, potentially affecting MIP-3β/CCL19. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Regulates immune responses, could indirectly affect MIP-3β/CCL19 expression. | ||||||