mGluR Substrates
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TCN 238 | 125404-04-8 | sc-362803 sc-362803A | 10 mg 50 mg | $155.00 $620.00 | ||
TCN 238 is a selective modulator of metabotropic glutamate receptors, distinguished by its unique structural features that promote targeted interactions with receptor domains. This compound exhibits a distinct mechanism of action, influencing receptor conformations and enhancing downstream signaling cascades. Its reaction kinetics suggest a nuanced engagement with the receptor, allowing for precise modulation of synaptic activity. TCN 238's ability to stabilize specific receptor states further underscores its role in fine-tuning neural communication. | ||||||
(1S,3S)-homo-ACPD | 194785-78-9 | sc-206307 | 5 mg | $315.00 | ||
(1S,3S)-homo-ACPD is a potent allosteric modulator of metabotropic glutamate receptors, characterized by its ability to selectively bind to specific receptor sites, thereby altering their functional dynamics. This compound engages in unique molecular interactions that facilitate the activation of intracellular signaling pathways, leading to enhanced synaptic plasticity. Its distinct reaction kinetics allow for a finely-tuned modulation of receptor activity, contributing to the regulation of excitatory neurotransmission. | ||||||
LY 487379 hydrochloride | 353229-59-1 | sc-204065 sc-204065A | 10 mg 50 mg | $145.00 $615.00 | ||
LY 487379 hydrochloride is a selective allosteric modulator of metabotropic glutamate receptors, exhibiting unique binding properties that influence receptor conformation. This compound interacts with specific allosteric sites, promoting distinct signaling cascades that modulate neuronal excitability. Its kinetic profile allows for precise temporal control over receptor activation, enhancing the understanding of synaptic mechanisms and providing insights into glutamatergic transmission dynamics. | ||||||
VU 0357121 | 433967-28-3 | sc-364645 sc-364645A | 10 mg 50 mg | $145.00 $615.00 | ||
VU 0357121 is a potent allosteric modulator of metabotropic glutamate receptors, characterized by its ability to stabilize specific receptor conformations. This compound engages with unique binding sites, facilitating selective signaling pathways that influence intracellular calcium levels and neurotransmitter release. Its distinct interaction dynamics contribute to a nuanced understanding of synaptic plasticity and receptor desensitization, offering insights into the modulation of excitatory neurotransmission. | ||||||
CBiPES hydrochloride | 856702-40-4 | sc-358830 sc-358830A | 10 mg 50 mg | $145.00 $645.00 | ||
CBiPES hydrochloride acts as a selective modulator of metabotropic glutamate receptors, exhibiting unique binding affinities that alter receptor dynamics. Its interactions promote distinct conformational changes, influencing downstream signaling cascades and intracellular responses. The compound's kinetic profile reveals rapid association and dissociation rates, allowing for fine-tuning of synaptic responses. This specificity in receptor engagement enhances our understanding of glutamatergic signaling mechanisms. | ||||||
BINA | 866823-73-6 | sc-361121 sc-361121A | 10 mg 50 mg | $134.00 $756.00 | 1 | |
BINA functions as a selective modulator of metabotropic glutamate receptors, characterized by its ability to stabilize specific receptor conformations. This stabilization leads to altered G-protein coupling efficiency, impacting intracellular calcium signaling pathways. The compound exhibits unique allosteric properties, enhancing receptor sensitivity to endogenous ligands. Its distinct interaction kinetics facilitate nuanced regulation of synaptic plasticity, providing insights into glutamate-mediated neurotransmission. | ||||||
VU 0361737 | 1161205-04-4 | sc-301976 sc-301976A | 10 mg 50 mg | $115.00 $440.00 | ||
VU 0361737 acts as a selective modulator of metabotropic glutamate receptors, exhibiting unique binding dynamics that influence receptor activation states. Its distinct molecular interactions promote a shift in receptor conformational landscape, enhancing downstream signaling cascades. The compound's ability to fine-tune G-protein interactions allows for precise modulation of synaptic responses, contributing to a deeper understanding of glutamate's role in neural communication and plasticity. | ||||||
L-γ-Carboxyglutamic acid | 53861-57-7 | sc-295277 sc-295277A | 10 mg 50 mg | $402.00 $1047.00 | ||
L-γ-Carboxyglutamic acid serves as a potent allosteric modulator of metabotropic glutamate receptors, engaging in specific hydrogen bonding and ionic interactions that stabilize receptor conformations. This compound influences the kinetics of receptor activation, facilitating nuanced signaling pathways. Its unique structural features enable selective engagement with G-proteins, thereby altering intracellular calcium dynamics and impacting synaptic efficacy and neuronal excitability. | ||||||