mGluR Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
CPCCOEt | 179067-99-3 | sc-200481 sc-200481A | 10 mg 50 mg | $138.00 $587.00 | 1 | |
CPCCOEt acts as a selective modulator of metabotropic glutamate receptors, distinguished by its ability to engage in specific hydrogen bonding interactions that enhance receptor affinity. Its unique structural conformation facilitates distinct allosteric modulation, influencing receptor dynamics and signaling pathways. The compound's kinetic profile allows for rapid receptor activation, providing insights into synaptic transmission and neuronal communication mechanisms. | ||||||
YM 298198 hydrochloride | 748758-45-4 | sc-361412 sc-361412A | 10 mg 50 mg | $179.00 $760.00 | ||
YM 298198 hydrochloride is a selective modulator of metabotropic glutamate receptors, characterized by its unique ability to stabilize receptor conformations through specific hydrophobic interactions. This compound exhibits distinct binding kinetics, allowing for nuanced regulation of receptor activity. Its structural features promote selective engagement with receptor subtypes, influencing downstream signaling cascades and contributing to the modulation of synaptic plasticity. | ||||||
DL-2-Amino-3-phosphonopropionic acid (AP3) | 20263-06-3 | sc-200433 | 100 mg | $117.00 | ||
DL-2-Amino-3-phosphonopropionic acid (AP3) acts as a competitive antagonist at metabotropic glutamate receptors, exhibiting a unique ability to disrupt glutamate-mediated signaling. Its structural conformation allows for specific interactions with receptor sites, influencing ion channel activity and intracellular calcium levels. The compound's kinetics reveal a rapid onset of action, providing a distinct temporal profile in receptor modulation, which can affect synaptic transmission dynamics. | ||||||
(RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine | sc-222264 | 5 mg | $60.00 | |||
(RS)-α-Methyl-3-carboxy-4-hydroxyphenylglycine functions as a selective modulator of metabotropic glutamate receptors, showcasing a unique binding affinity that alters receptor conformation. This compound engages in specific hydrogen bonding and hydrophobic interactions, influencing downstream signaling pathways. Its kinetic profile indicates a gradual onset, allowing for sustained modulation of synaptic plasticity, which can impact neuronal excitability and network dynamics. | ||||||
MPPG | 169209-65-8 | sc-203143 sc-203143A | 10 mg 50 mg | $175.00 $739.00 | ||
MPP-G is a potent modulator of metabotropic glutamate receptors, characterized by its ability to selectively influence receptor activity through unique allosteric interactions. This compound exhibits distinct binding kinetics, promoting conformational changes that enhance or inhibit receptor signaling. Its molecular structure facilitates specific electrostatic interactions, which can fine-tune intracellular calcium signaling pathways, ultimately affecting synaptic transmission and neuronal communication. | ||||||
Desmethyl-YM 298198 | 299901-57-8 | sc-361167 sc-361167A | 10 mg 50 mg | $185.00 $781.00 | ||
Desmethyl-YM 298198 acts as a selective modulator of metabotropic glutamate receptors, showcasing unique binding properties that alter receptor dynamics. Its molecular architecture allows for specific hydrophobic interactions, influencing receptor conformation and downstream signaling cascades. The compound's distinct reaction kinetics enable it to stabilize intermediate states, thereby modulating the activation threshold of associated pathways, which can lead to nuanced effects on cellular excitability and neurotransmitter release. | ||||||
(S)-MPPG (cyclic) | 201608-25-5 | sc-222284 | 1 mg | $45.00 | ||
(S)-MPPG (cyclic) is a selective modulator of metabotropic glutamate receptors, characterized by its unique cyclic structure that facilitates specific interactions with receptor sites. This compound exhibits distinct allosteric modulation, enhancing receptor sensitivity and altering ligand affinity. Its kinetic profile reveals a rapid onset of action, allowing for fine-tuning of synaptic transmission. Additionally, (S)-MPPG's conformational flexibility contributes to its ability to influence intracellular signaling pathways, impacting neuronal communication. | ||||||