BINA CAS: 866823-73-6
MF: C30H30O4
MW: 454.56
A selective positive allosteric modulator of mGluR-2.

BINA (CAS 866823-73-6)

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Alternate Names: Biphenyl-indanone A; 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biph enyl]-4-carboxylic acid
Application: BINA is a selective positive allosteric modulator of mGluR-2
CAS Number: 866823-73-6
Purity: ≥98%
Molecular Weight: 454.56
Molecular Formula: C30H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

BINA is a selective positive allosteric modulator of mGluR-2. This compound displays no effect on glutamate-induced activation of other mGluR types.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), ethanol (~0.2 mg/ml), and DMF (~1.6 mg/ml).
Storage :
Desiccate at room temperature
Melting Point :
238-241° C
Boiling Point :
~676.9° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
IC50 :
mGluR-2: EC5050 = 27.54 nM (human); Metabotropic glutamate receptor 2: EC5050 = 380 nM (rat)
pK Values :
pKa: 4.17 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
9868580
MDL Number :
MFCD19440914
SMILES :
CC1=C(C=C2CC(C(=O)C2=C1C)C3CCCC3)OCC4=CC=CC(=C4)C5=CC=C(C=C5)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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