MF: C30H30O4 MW: 454.56 A selective positive allosteric modulator of mGluR-2.
Protein-Interacting Inhibitors, Activators & Substrates
Protein Substrates, etc.
BINA (CAS 866823-73-6)
Biphenyl-indanone A; 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biph enyl]-4-carboxylic acid
BINA is a selective positive allosteric modulator of mGluR-2
C 30H 30O 4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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BINA is a selective positive allosteric modulator of mGluR-2. This compound displays no effect on glutamate-induced activation of other mGluR types.
Soluble in DMSO (100 mM), ethanol (~0.2 mg/ml), and DMF (~1.6 mg/ml).
Desiccate at room temperature
~676.9° C at 760 mmHg (Predicted)
20 D 1.63 (Predicted)
5050 = 27.54 nM (human); Metabotropic glutamate receptor 2: EC 5050 = 380 nM (rat)
a: 4.17 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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