MGC26647 Activators
MGC26647 Activators represents a group of compounds that are characterized by their ability to modulate the activity of the molecular entity denoted by the code MGC26647. The name itself does not conform to standard nomenclature for biochemical compounds or pharmaceutical agents, suggesting that it might be a proprietary or provisional designation used in a research context to describe a set of molecules with a specific mechanism of action. These activators are typically the subject of intense research and development due to their unique role in affecting the function of their target molecule.
In terms of their chemical properties, MGC26647 activators would likely exhibit a diverse range of structures, tailored to interact with the specific conformational sites of the MGC26647 molecule. The design of such activators would include consideration of the molecule's size, shape, electronic distribution, and the presence of specific functional groups that can engage in interactions such as hydrogen bonding, hydrophobic effects, and van der Waals forces. The exact structure-activity relationships governing the efficacy of MGC26647 activators would depend on the precise biochemistry of the interaction between the activator and its target, which could involve inducing a conformational change in the target molecule or stabilizing it in an active form. The chemical synthesis of MGC26647 activators would likely involve complex organic reactions, potentially requiring multiple steps to achieve the desired specificity and high affinity for the MGC26647 molecule.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, thereby increasing levels of cAMP in the cell. Elevated cAMP activates PKA (protein kinase A), which can phosphorylate and thus enhance the activity of MGC26647 by promoting its role in signal transduction pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA directly activates protein kinase C (PKC), which is involved in the regulation of MGC26647 by phosphorylating it or associated proteins, leading to enhanced activity of MGC26647 in cell signaling cascades. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels, activating calcium-dependent protein kinases that may phosphorylate MGC26647, thus enhancing its activity in calcium signaling pathways. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a beta-adrenergic agonist that activates adenylate cyclase, leading to increased cAMP and activation of PKA. This cascade can enhance the activity of MGC26647 through cAMP-dependent signaling. | ||||||
(±)-S-Nitroso-N-acetylpenicillamine | 79032-48-7 | sc-200319B sc-200319 sc-200319A | 10 mg 20 mg 100 mg | $74.00 $114.00 $374.00 | 18 | |
SNAP releases nitric oxide (NO), which activates guanylate cyclase and increases levels of cGMP, a secondary messenger that can engage signaling pathways leading to the activation of MGC26647. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $108.00 $169.00 $295.00 $561.00 $835.00 | 2 | |
8-Br-cAMP is a cell-permeable cAMP analog that activates PKA, promoting phosphorylation events that may enhance the functional activity of MGC26647 as part of cAMP-dependent processes. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Calcimycin is a calcium ionophore that increases intracellular calcium, thereby activating calmodulin-dependent kinases that could phosphorylate MGC26647, leading to its enhanced activity in calcium-mediated signaling. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is known to modulate several signaling pathways by inhibiting certain kinases, which can shift the equilibrium of cellular signaling in a way that promotes the activation of MGC26647. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Anisomycin is a protein synthesis inhibitor that activates stress-activated protein kinases (SAPKs), which are involved in signaling cascades that can lead to the enhancement of MGC26647 activity during cellular stress responses. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that can modulate downstream AKT signaling, potentially altering the phosphorylation status of MGC26647 or associated proteins and leading to its enhanced activity. | ||||||