Date published: 2026-3-3

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MGC1203 Activators

The chemical class known as MGC1203 Activators refers to a specific group of compounds identified for their capability to modulate the activity of the MGC1203 gene. MGC1203, or Metastasis Associated in Colon Cancer 1 (MACC1) Gene Homolog, is a gene that has been implicated in cancer progression and metastasis. It encodes a protein that acts as a transcriptional activator and is involved in various cellular processes, including cell proliferation, migration, invasion, and apoptosis. The exact function of MGC1203 is not fully elucidated, but it is believed to play a crucial role in promoting tumor progression and metastasis in several cancer types. Activators of MGC1203 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.

Characterizing compounds as MGC1203 Activators typically involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the MGC1203 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for MGC1203 gene expression, or modulating post-translational modifications of the MGC1203 protein. Understanding the molecular mechanisms underlying MGC1203 activation by these compounds is crucial for elucidating the roles of MGC1203 in cancer progression and metastasis. Further research into MGC1203 Activators may provide insights into novel cellular pathways involved in cancer development and metastatic spread and contribute to a deeper understanding of MGC1203's function in cancer biology.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can regulate gene expression via retinoic acid receptors, potentially affecting CCDC28B expression.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylate cyclase, increasing cAMP levels, which can modulate the expression of various genes.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C, which can influence gene expression patterns in the cell.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, it can alter chromatin structure and potentially upregulate gene expression, including CCDC28B.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This DNA methyltransferase inhibitor could affect the methylation status of genes, altering their expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

As a histone deacetylase inhibitor, it can affect gene expression by changing chromatin accessibility.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Another histone deacetylase inhibitor that could theoretically increase CCDC28B expression by affecting chromatin structure.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

It binds to DNA and can inhibit transcription factor binding, potentially altering gene expression profiles.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Affects glycogen synthase kinase-3 activity and could influence the expression of various genes.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG has multiple effects on cellular processes and could modulate gene expression through epigenetic mechanisms.