The chemical class known as MGC1203 Activators refers to a specific group of compounds identified for their capability to modulate the activity of the MGC1203 gene. MGC1203, or Metastasis Associated in Colon Cancer 1 (MACC1) Gene Homolog, is a gene that has been implicated in cancer progression and metastasis. It encodes a protein that acts as a transcriptional activator and is involved in various cellular processes, including cell proliferation, migration, invasion, and apoptosis. The exact function of MGC1203 is not fully elucidated, but it is believed to play a crucial role in promoting tumor progression and metastasis in several cancer types. Activators of MGC1203 are substances capable of enhancing the expression or function of this gene, potentially influencing downstream cellular pathways and biological responses associated with its activity.
Characterizing compounds as MGC1203 Activators typically involves comprehensive screening processes aimed at evaluating their ability to interact with regulatory elements of the MGC1203 gene or modulate the activity of proteins associated with its expression or function. These activators may operate through diverse mechanisms, such as binding to specific DNA sequences within the gene promoter region, regulating the activity of transcription factors responsible for MGC1203 gene expression, or modulating post-translational modifications of the MGC1203 protein. Understanding the molecular mechanisms underlying MGC1203 activation by these compounds is crucial for elucidating the roles of MGC1203 in cancer progression and metastasis. Further research into MGC1203 Activators may provide insights into novel cellular pathways involved in cancer development and metastatic spread and contribute to a deeper understanding of MGC1203's function in cancer biology.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can regulate gene expression via retinoic acid receptors, potentially affecting CCDC28B expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, increasing cAMP levels, which can modulate the expression of various genes. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, which can influence gene expression patterns in the cell. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, it can alter chromatin structure and potentially upregulate gene expression, including CCDC28B. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor could affect the methylation status of genes, altering their expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
As a histone deacetylase inhibitor, it can affect gene expression by changing chromatin accessibility. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Another histone deacetylase inhibitor that could theoretically increase CCDC28B expression by affecting chromatin structure. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
It binds to DNA and can inhibit transcription factor binding, potentially altering gene expression profiles. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase-3 activity and could influence the expression of various genes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG has multiple effects on cellular processes and could modulate gene expression through epigenetic mechanisms. | ||||||