Date published: 2026-4-24

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MFSD6L Activators

1,1-Dimethylbiguanide, Hydrochloride and Phenformin, by triggering AMPK, drive cellular energy balance towards a state that supports the functional readiness of MFSD6L. AICAR, mimicking AMP's structure, taps into this energy-sensing pathway, ensuring that the energy status within the cell is conducive to the mobilization of MFSD6L. Berberine, on the other hand, while also an AMPK activator, introduces additional layers of metabolic modulation, which can influence the protein's activity.

SIRT1 activators like Resveratrol and SRT1720 delve deeper into the cell's metabolic core, enhancing mitochondrial function, which is intrinsically tied to the overall metabolic activity. This improvement in energy efficiency can echo through to MFSD6L, facilitating its operational capacity. PPAR agonists such as Pioglitazone, Rosiglitazone, GW501516, and Ciglitazone recalibrate lipid metabolism, which is a crucial factor for the membrane-bound MFSD6L, potentially altering its dynamics and function. Forskolin stands out by amplifying cAMP levels, thereby influencing various cAMP-dependent processes that can cascade down to affect the workings of MFSD6L. Quercetin, with its versatile impact on cellular mechanisms, including those modulated by AMPK and SIRT1, suggests that a wide array of signaling pathways can converge to modulate the activity of MFSD6L.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

AMPK pathway activator that can enhance glucose transport and may affect MFSD6L by modulating cellular energy status.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AMP analog that activates AMPK and may influence MFSD6L activity by altering cellular energy balance.

Phenformin Hydrochloride

834-28-6sc-219590
10 g
$119.00
4
(1)

AMPK activator that can indirectly influence MFSD6L activity through modulation of cellular metabolism.

Berberine

2086-83-1sc-507337
250 mg
$92.00
1
(0)

Plant alkaloid that can activate AMPK, potentially affecting MFSD6L by altering metabolic processes.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

SIRT1 activator that can support cellular energy balance and may indirectly affect MFSD6L function.

SRT1720

1001645-58-4sc-364624
sc-364624A
5 mg
10 mg
$197.00
$364.00
13
(1)

SIRT1 activator that can enhance mitochondrial function and may indirectly influence MFSD6L activity by improving cellular energy status.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

PPAR-γ agonist that can alter lipid metabolism and may have an indirect effect on MFSD6L activity by modifying the cellular lipid environment.

Rosiglitazone

122320-73-4sc-202795
sc-202795A
sc-202795C
sc-202795D
sc-202795B
25 mg
100 mg
500 mg
1 g
5 g
$120.00
$326.00
$634.00
$947.00
$1259.00
38
(1)

PPAR-γ agonist with potential to alter MFSD6L activity by affecting lipid handling in cells.

GW501516

317318-70-0sc-202642
sc-202642A
1 mg
5 mg
$82.00
$179.00
28
(3)

PPAR-δ agonist that can change energy usage patterns in cells and may indirectly affect MFSD6L function.

Ciglitazone

74772-77-3sc-200902
sc-200902A
5 mg
25 mg
$104.00
$428.00
10
(1)

PPAR-γ agonist that can affect glucose and lipid metabolism, potentially altering MFSD6L activity through metabolic changes.