MEL-28 inhibitors represent a distinctive class of compounds targeting the MEL-28 protein, which is implicated in various cellular processes, including RNA metabolism and the regulation of gene expression. These inhibitors are designed to interfere with the normal function of MEL-28, primarily by binding to specific sites on the protein, thus preventing its interaction with other molecular partners. The structural diversity of MEL-28 inhibitors allows for the fine-tuning of their binding affinity and specificity, making them valuable tools in biochemical research. Through this targeted inhibition, researchers can dissect the functional roles of MEL-28 in cellular pathways, leading to a better understanding of its contributions to biological systems.
In experimental settings, MEL-28 inhibitors are utilized to explore the protein's involvement in processes such as mRNA transport, splicing, and translation. By inhibiting MEL-28, scientists can observe the resulting changes in RNA dynamics and gene regulation, providing insights into the molecular mechanisms that govern cellular function. The study of MEL-28 inhibitors also aids in elucidating the broader implications of RNA-binding proteins in cellular physiology, including how they respond to various stimuli and stressors. As research continues, MEL-28 inhibitors serve as critical reagents for advancing knowledge in molecular biology, particularly in understanding the complex interplay between proteins, RNA, and the regulatory networks that sustain cellular life.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $107.00 $416.00 $1248.00 | 35 | |
Inhibits nuclear export, potentially influencing nuclear transport processes related to MEL-28/ELYS. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, possibly impacting MEL-28/ELYS activity in mitosis. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, alters chromatin structure, possibly influencing MEL-28/ELYS. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Affect chromatin organization, potentially impacting MEL-28/ELYS. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Influence cell cycle regulation, potentially affecting MEL-28/ELYS activity. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
Inhibit Aurora kinases, could impact MEL-28/ELYS function in cell cycle. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
Induce DNA damage, potentially influencing MEL-28/ELYS in cell cycle and chromatin organization. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Disrupts microtubule polymerization, potentially impacting MEL-28/ELYS in mitosis. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
Affect chromatin and transcription, potentially influencing MEL-28/ELYS. | ||||||