Med22 Activators
Mediator complex subunit 22 (Med22), also known as Sur2, is a protein that in humans is encoded by the MED22 gene. It is a component of the multi-subunit Mediator complex, which plays a critical role in the regulation of gene transcription.The Mediator complex serves as a bridge, facilitating communication between the transcription machinery, including RNA polymerase II, and transcription factors that bind to specific DNA sequences. This interaction helps initiate the transcription process, thereby controlling the expression of genes.
Med22 is one of the smaller subunits of the Mediator complex, but it plays a crucial role in the assembly and integrity of the complex. It is a component of the head module of the Mediator complex, which is essential for interactions with RNA polymerase II.Alterations in the function or expression of Mediator complex subunits, including Med22, can significantly affect gene transcription, leading to various diseases. For instance, mutations in different Mediator subunits have been associated with diverse conditions ranging from developmental disorders to cancer.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, might indirectly affect MED22 by changing DNA methylation patterns and transcriptional regulation. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor, potentially affecting MED22 function. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Known to affect multiple cellular processes, could indirectly influence MED22 activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A compound from turmeric that impacts various cellular processes, including transcriptional regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in gene transcription and differentiation, could indirectly affect MED22. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
A tyrosine kinase inhibitor, could impact transcription factor activity and indirectly affect MED22. | ||||||
Garcinol | 78824-30-3 | sc-200891 sc-200891A | 10 mg 50 mg | $124.00 $502.00 | 13 | |
An inhibitor of histone acetyltransferases, potentially influencing MED22 function. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
A histone deacetylase inhibitor, might have indirect effects on MED22 activity. | ||||||