Med19 Activators
Med19 Activators includes a diverse group of chemical compounds, primarily centered around modifying chromatin structure and influencing transcription regulation, impacting the function of Med19. Trichostatin A, SAHA, and RGFP966's action on chromatin remodeling can create a more transcriptionally active chromatin state, enhancing the functional activity of Med19 in the transcription regulation process. Similarly, 5-Azacytidine and C646, by altering DNA methylation and histone acetylation respectively, might indirectly influence Med19's role in gene expression modulation.
Furthermore, compounds like JQ1, I-BET151, and PF-6463922, which inhibit BET bromodomains, could affect Med19 by altering the accessibility of transcriptional machinery to chromatin. This alteration might enhance Med19's involvement in the regulation of gene transcription. Additionally, BIX-01294 and MTA1, targeting histone methyltransferase and mRNA methylation respectively, represent another avenue through which Med19's activity could be modulated. By influencing these epigenetic mechanisms, these compounds might indirectly enhance Med19's role in the complex process of transcription regulation. Quercetin and MS-275 (Entinostat) also contribute to this class, affecting transcription factors and chromatin structure, thereby impacting Med19's function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor, TSA can influence chromatin structure and transcription, potentially affecting Med19's role in transcription regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor, it alters DNA methylation, potentially influencing Med19's function in gene expression regulation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another histone deacetylase inhibitor, SAHA could impact Med19's function by altering chromatin structure and thus transcriptional regulation. | ||||||
RGFP966 | 1357389-11-7 | sc-507300 | 5 mg | $115.00 | ||
An HDAC3 inhibitor, it could indirectly affect Med19's role in the Mediator complex by influencing gene expression and chromatin architecture. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
A p300/CBP histone acetyltransferase inhibitor, potentially impacting Med19's function in transcription regulation by altering histone acetylation. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
A G9a histone methyltransferase inhibitor, it may influence chromatin dynamics and transcriptional regulation, potentially affecting Med19’s activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of the METTL3-METTL14 complex, potentially impacting mRNA methylation and transcription regulation, thereby affecting Med19's function. | ||||||
Lorlatinib | 1454846-35-5 | sc-507437 | 5 mg | $135.00 | ||
A BET bromodomain inhibitor, could modulate transcription, potentially influencing Med19's role in the transcriptional regulation process. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid with various cellular effects, including potential impacts on transcription factors and chromatin structure, possibly influencing Med19’s function. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
A selective HDAC inhibitor, MS-275 might affect chromatin remodeling and transcription, potentially impacting the activity of Med19 in transcription regulation. | ||||||