Measles H Inhibitors refers to a distinct class of chemical compounds specifically designed to target and impede the function of the hemagglutinin (H) glycoprotein of the measles virus. Measles, caused by the measles virus (MeV), is a highly contagious infectious disease that primarily affects children and can lead to severe complications. The H glycoprotein plays a crucial role in the initial stages of the viral life cycle by facilitating viral entry into host cells. Measles H Inhibitors often exhibit a targeted and precise configuration that allows them to selectively bind to the H glycoprotein, interfering with its ability to recognize and engage host cell receptors.
This targeted interference at the molecular level holds promise for the development of antiviral strategies against measles infection. The rational design of these inhibitors involves a thorough understanding of the molecular interactions between the viral glycoprotein and host cell receptors, enabling the creation of compounds that effectively obstruct the viral entry process. Ongoing research in this field aims to further elucidate the mechanisms of viral entry and improve the design of Measles H Inhibitors, contributing to the broader effort to combat infectious diseases caused by the measles virus.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $62.00 $108.00 $210.00 | 1 | |
Ribavirin is a nucleoside analogue that can interfere with viral RNA synthesis, potentially affecting the replication of the measles virus. | ||||||
1-Adamantylamine | 768-94-5 | sc-251475 sc-251475A | 1 g 25 g | $38.00 $144.00 | ||
Amantadine can disrupt viral uncoating, although its action is more specific to influenza virus; its effect on measles virus replication is undetermined. | ||||||
Suramin sodium | 129-46-4 | sc-507209 sc-507209F sc-507209A sc-507209B sc-507209C sc-507209D sc-507209E | 50 mg 100 mg 250 mg 1 g 10 g 25 g 50 g | $149.00 $210.00 $714.00 $2550.00 $10750.00 $21410.00 $40290.00 | 5 | |
Suramin is known to inhibit cell entry of some viruses by interfering with cellular receptors or factors required for viral entry. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine is a weak base and can change the pH of intracellular compartments, potentially affecting virus-cell fusion. | ||||||
Ruxolitinib | 941678-49-5 | sc-364729 sc-364729A sc-364729A-CW | 5 mg 25 mg 25 mg | $246.00 $490.00 $536.00 | 16 | |
JAK inhibitors can modulate the immune response and might disrupt signaling required for efficient viral replication or assembly. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, potentially reducing guanine nucleotides and affecting viral RNA synthesis. | ||||||
Nitazoxanide | 55981-09-4 | sc-212397 | 10 mg | $122.00 | 1 | |
Nitazoxanide has broad-spectrum antiviral activity, possibly by interfering with the maturation of viral proteins. | ||||||
Ivermectin | 70288-86-7 | sc-203609 sc-203609A | 100 mg 1 g | $56.00 $75.00 | 2 | |
Ivermectin can inhibit importin α/β1 heterodimer, potentially impeding nuclear transport of viral proteins. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $32.00 $210.00 $720.00 $1128.00 $2302.00 $3066.00 $5106.00 | 22 | |
Apigenin has been shown to have antiviral properties and may disrupt protein synthesis necessary for viral replication. | ||||||