Date published: 2025-12-17

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1-Adamantylamine (CAS 768-94-5)

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Alternate Names:
1-Aminoadamantane
CAS Number:
768-94-5
Purity:
>99%
Molecular Weight:
151.25
Molecular Formula:
C10H17N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1-Adamantylamine is a compound of interest in materials science and organic synthesis due to its bulky adamantane structure, which provides unique steric properties. It is utilized as a building block in the creation of polymers and novel organic materials where rigidity and high thermal stability are desired. Researchers also employ 1-Adamantylamine in the synthesis of dendrimers and other macromolecules that require a well-defined three-dimensional architecture. Its primary amine group allows for straightforward functionalization, enabling the introduction of various substituents to modify the compound′s physical and chemical characteristics. Studies involving 1-Adamantylamine often explore its role in the design of host-guest systems and its interactions with other molecules, which is valuable in the development of new supramolecular assemblies.


1-Adamantylamine (CAS 768-94-5) References

  1. Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.  |  Halámiková, A., et al. 2008. J Inorg Biochem. 102: 1077-89. PMID: 18237783
  2. 1-Adamantylamine a simple urine marker for screening for third generation adamantyl-type synthetic cannabinoids by ultra-performance liquid chromatography tandem mass spectrometry.  |  Ford, LT. and Berg, JD. 2016. Ann Clin Biochem. 53: 640-646. PMID: 26748105
  3. Organic Functionalized Graphene Oxide Behavior in Water.  |  Kim, C., et al. 2020. Nanomaterials (Basel). 10: PMID: 32599799
  4. Design, synthesis and antimycobacterial evaluation of novel adamantane and adamantanol analogues effective against drug-resistant tuberculosis.  |  Alsayed, SSR., et al. 2021. Bioorg Chem. 106: 104486. PMID: 33276981
  5. Facile synthesis and antimycobacterial activity of isoniazid, pyrazinamide and ciprofloxacin derivatives.  |  Alsayed, SSR., et al. 2021. Chem Biol Drug Des. 97: 1137-1150. PMID: 33638304
  6. Synthesis and antitumour evaluation of indole-2-carboxamides against paediatric brain cancer cells.  |  Alsayed, SSR., et al. 2021. RSC Med Chem. 12: 1910-1925. PMID: 34825187
  7. Spectroscopic study of L-DOPA and dopamine binding on novel gold nanoparticles towards more efficient drug-delivery system for Parkinson's disease.  |  Kalčec, N., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 268: 120707. PMID: 34902692
  8. Immuno-affinitive supramolecular magnetic nanoparticles incorporating cucurbit[8]uril-mediated ternary host-guest complexation structures for high-efficient small extracellular vesicle enrichment.  |  Zhu, N., et al. 2022. J Colloid Interface Sci. 611: 462-471. PMID: 34968965
  9. Size compatibility and concentration dependent supramolecular host-guest interactions at interfaces.  |  Park, J., et al. 2022. Nat Commun. 13: 112. PMID: 35013244
  10. A Polyanionic Strategy to Modify the Perovskite Grain Boundary for a Larger Switching Ratio in Flexible Woven Resistive Random-Access Memories.  |  Shen, J., et al. 2022. ACS Appl Mater Interfaces. 14: 44652-44664. PMID: 36125291
  11. Quantum DFT methods to explore the interaction of 1-Adamantylamine with pristine, and P, As, Al, and Ga doped BN nanotubes.  |  Nemati-Kande, E., et al. 2022. Sci Rep. 12: 19972. PMID: 36402905
  12. Direct Activation of the C(sp3)-NH2 Bond of Primary Aliphatic Alkylamines by a High-Valent CoIII,IV2(μ-O)2 Diamond Core Complex.  |  Li, Y., et al. 2023. J Am Chem Soc. 145: 2690-2697. PMID: 36689463
  13. Studies on the nature and pressure evolution of phase transitions in 1-adamantylamine and 1-adamantanol.  |  Jesionek, P., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 299: 122794. PMID: 37167743

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1-Adamantylamine, 1 g

sc-251475
1 g
$38.00

1-Adamantylamine, 25 g

sc-251475A
25 g
$144.00