MC4-R Activators
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ro 27-3225 trifluoroacetate salt | sc-311523 | 1 mg | $190.00 | |||
Ro 27-3225 trifluoroacetate salt acts as a selective agonist for the MC4-R receptor, showcasing a distinct binding affinity that promotes unique conformational changes in the receptor structure. This interaction triggers a series of downstream signaling events, primarily through the activation of G-proteins, which modulate intracellular calcium levels. The compound's trifluoroacetate moiety enhances solubility and stability, facilitating its engagement with the receptor and influencing metabolic pathways. | ||||||
THIQ | 312637-48-2 | sc-204343 sc-204343A | 1 mg 10 mg | $260.00 $1200.00 | 1 | |
THIQ functions as a selective modulator of the MC4-R receptor, exhibiting a unique interaction profile that stabilizes specific receptor conformations. This compound engages in intricate molecular dynamics, influencing the receptor's affinity for G-proteins and altering downstream signaling cascades. Its structural features promote enhanced receptor-ligand interactions, leading to distinct alterations in cellular signaling pathways and metabolic regulation. The compound's unique properties contribute to its role in receptor modulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, extracted from the plant Coleus forskohlii, activates adenylyl cyclase, leading to an increase in cAMP levels. Elevated cAMP can enhance G protein-coupled receptor signaling, including MC4-R, by potentiating the pathway downstream of the receptor activation. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine, a central nervous system stimulant, can inhibit phosphodiesterases, thus preventing cAMP degradation. This increase in cAMP can enhance MC4-R signaling indirectly, as cAMP is a second messenger in MC4-R pathways. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline, similar to caffeine, acts as a phosphodiesterase inhibitor, leading to increased cAMP levels. This elevation can indirectly influence MC4-R signaling pathways, enhancing their activity. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram, a selective phosphodiesterase-4 inhibitor, leads to increased cAMP levels in cells. Elevated cAMP can indirectly enhance MC4-R activity by potentiating the signaling pathways downstream of the receptor. | ||||||
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol, a non-selective beta-adrenergic agonist, can increase cAMP levels via beta-adrenergic receptors, indirectly influencing MC4-R signaling through enhanced G protein-coupled receptor signaling. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine, a hormone and a neurotransmitter, acts on various adrenergic receptors to increase cAMP levels. This indirect action can enhance MC4-R signaling pathways. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $96.00 $160.00 $240.00 $405.00 | 26 | |
Capsaicin, the active component in chili peppers, can influence various metabolic processes. While its direct action on MC4-R is not clear, its role in energy metabolism suggests it may indirectly affect MC4-R signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Green Tea Extract, containing compounds like EGCG, can influence metabolic pathways. These compounds may indirectly affect MC4-R signaling through their roles in energy metabolism and cAMP modulation. | ||||||