MBD3L1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Histone deacetylase inhibitor that increases acetylation of histones, leading to a more open chromatin structure and often increased transcription. Given MBD3L1's role in chromatin organization, Trichostatin A could lead to the inhibition of MBD3L1's ability to bind methylated DNA by altering the chromatin state. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
DNA methyltransferase inhibitor that reduces DNA methylation. MBD3L1, which binds to methylated DNA, would have fewer binding sites available, potentially decreasing its functional activity. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
DNA methyltransferase inhibitor that prevents DNA methylation without the cytotoxicity of nucleoside analogs. Reduced DNA methylation would decrease MBD3L1's ability to bind to methylated DNA. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Antitumor antibiotic that binds to GC-rich sequences in DNA, possibly preventing MBD3L1 from interacting with its usual binding sites if they overlap with GC-rich regions. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Known as an antimalarial drug, it intercalates into DNA, which could disrupt MBD3L1's ability to bind methylated DNA due to structural interference. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid that is known to inhibit DNA methyltransferases, leading to decreased methylation and potentially decreased MBD3L1 binding to methylated DNA regions. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 (free base) | sc-202651 | 5 mg | $151.00 | 4 | |
Histone lysine methyltransferase inhibitor, targeting G9a and GLP, which modifies histones at MBD3L1 binding sites, potentially altering its ability to bind DNA. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Histone deacetylase inhibitor that can alter chromatin structure, potentially decreasing MBD3L1's ability to bind to its methylated DNA targets effectively. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
DNA methyltransferase inhibitor that leads to DNA demethylation, potentially reducing MBD3L1's ability to bind its target DNA sequences. | ||||||
Hydralazine-15N4 Hydrochloride | 304-20-1 (unlabeled) | sc-490605 | 1 mg | $480.00 | ||
A vasodilator that can also inhibit DNA methylation, thus potentially reducing MBD3L1's functional activity by decreasing its target DNA methylation levels. | ||||||