MAO-B Activators
The chemical class MAO-B Activators comprises a diverse range of compounds that may indirectly influence the activity of the Monoamine Oxidase B enzyme. MAO-B plays a critical role in the regulation of neurotransmitter levels, especially dopamine, in the brain. While direct activators of MAO-B are not well-documented, these compounds have the ability to modulate MAO-B activity through indirect mechanisms. Several compounds in this class, such as Selegiline and Rasagiline, are known irreversible MAO-B inhibitors By inhibiting MAO-B, they indirectly impact its activity by disrupting the breakdown of neurotransmitters like dopamine, resulting in increased neurotransmitter levels in the brain.
Other compounds, including Resveratrol, Curcumin, Puerarin, Quercetin, Nicotinamide, Tocopherol, Ginsenosides, Hesperidin, EGCG, and Naringin, have neuroprotective and antioxidant properties. They may influence MAO-B indirectly by affecting signaling pathways related to neuroprotection, oxidative stress, and neuroinflammation. These compounds offer avenues for modulating MAO-B expression or activity, thereby contributing to the regulation of neurotransmitter levels in the brain. In summary, the MAO-B Activators class represents a collection of compounds with diverse mechanisms of action, all of which have the ability to indirectly influence MAO-B activity. While their specific impact on MAO-B regulation requires further empirical investigation, these compounds offer promising avenues for research into the complex regulation of neurotransmitter levels and their implications for neurobiology and neuroprotection.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in red wine, has been shown to have neuroprotective effects. It may activate MAO-B indirectly by affecting signaling pathways related to neuroprotection and oxidative stress, possibly impacting its expression or activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a component of turmeric, possesses anti-inflammatory and antioxidant properties. Its influence on pathways related to neuroinflammation and oxidative stress may indirectly activate MAO-B activity in the brain. | ||||||
Puerarin | 3681-99-0 | sc-202301 sc-202301A | 5 mg 100 mg | $132.00 $209.00 | 1 | |
Puerarin, found in Kudzu root, has neuroprotective properties. It may activate MAO-B indirectly by modulating signaling pathways involved in neuroprotection and neurotransmitter regulation, potentially activating MAO-B expression or function. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid with antioxidant and anti-inflammatory properties. It may activate MAO-B indirectly by affecting pathways related to oxidative stress and neuroinflammation, potentially modulating MAO-B expression or activity. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide is a form of vitamin B3 with neuroprotective effects. It may indirectly activate MAO-B by affecting pathways related to neuroprotection and neurotransmitter regulation, potentially impacting its expression or activity. | ||||||
DL-α-Tocopherol | 10191-41-0 | sc-294383 sc-294383A sc-294383B sc-294383C | 5 g 25 g 100 g 500 g | $26.00 $52.00 $124.00 $326.00 | 3 | |
DL-α-Tocopherol has antioxidant properties. It may activate MAO-B indirectly by modulating oxidative stress-related pathways in the brain, potentially influencing MAO-B expression or function. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $82.00 $204.00 | 5 | |
Hesperidin is a flavonoid with antioxidant and anti-inflammatory effects. It may indirectly activate MAO-B by modulating pathways related to oxidative stress and neuroinflammation, potentially influencing MAO-B expression or activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, found in green tea, has antioxidant and neuroprotective properties. It may activate MAO-B indirectly by affecting pathways related to neuroprotection and neurotransmitter regulation, potentially impacting its expression or activity. | ||||||
Naringin | 10236-47-2 | sc-203443 sc-203443A | 25 g 50 g | $45.00 $101.00 | 7 | |
Naringin, a flavonoid in citrus fruits, has antioxidant and anti-inflammatory effects. It may indirectly activate MAO-B by modulating pathways related to oxidative stress and neuroinflammation, potentially influencing MAO-B expression or activity. | ||||||