MAO-B Inhibitors
Items 1 to 10 of 25 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quinacrine, Dihydrochloride | 69-05-6 | sc-204222 sc-204222B sc-204222A sc-204222C sc-204222D | 100 mg 1 g 5 g 200 g 300 g | $45.00 $56.00 $85.00 $3193.00 $4726.00 | 4 | |
Quinacrine, Dihydrochloride exhibits intriguing characteristics as a selective inhibitor of monoamine oxidase B (MAO-B). Its unique structural features enable it to engage in specific hydrogen bonding and hydrophobic interactions with the enzyme, influencing its catalytic efficiency. The compound's amphiphilic nature enhances its ability to traverse lipid membranes, potentially affecting the localization and activity of neurotransmitter substrates, thereby impacting their metabolic pathways. | ||||||
Tranylcypromine | 13492-01-8 | sc-200572 sc-200572A | 1 g 5 g | $172.00 $587.00 | 5 | |
Tranylcypromine functions as a selective inhibitor of monoamine oxidase B (MAO-B), showcasing distinctive molecular interactions that modulate enzyme activity. Its unique stereochemistry allows for effective binding to the active site, altering the enzyme's conformation and reaction kinetics. The compound's lipophilic characteristics facilitate its penetration into cellular environments, potentially influencing the dynamics of neurotransmitter degradation and the overall metabolic landscape within neuronal pathways. | ||||||
cis-Resveratrol Solution (in Ethanol) | 61434-67-1 | sc-205254 sc-205254A | 5 mg 10 mg | $120.00 $228.00 | 2 | |
Cis-Resveratrol Solution in ethanol exhibits intriguing interactions with monoamine oxidase B (MAO-B), characterized by its ability to stabilize enzyme conformations through specific hydrogen bonding and hydrophobic interactions. This compound's unique structural features enhance its affinity for the enzyme, leading to altered reaction kinetics. Additionally, its solubility in ethanol promotes efficient cellular uptake, potentially impacting metabolic processes and signaling pathways within the brain. | ||||||
Rasagiline | 136236-51-6 | sc-204875 sc-204875A | 25 mg 100 mg | $101.00 $210.00 | ||
Rasagiline functions as an irreversible MAO-B inhibitor by forming a covalent bond with the enzyme. This covalent modification renders the enzyme inactive and unable to perform its role in the degradation of neurotransmitters. | ||||||
Quinacrine Dihydrochloride Dihydrate | 6151-30-0 | sc-391946B sc-391946C sc-391946 sc-391946A | 1 g 5 g 10 g 25 g | $42.00 $84.00 $161.00 $338.00 | 1 | |
Quinacrine Dihydrochloride Dihydrate demonstrates notable interactions with monoamine oxidase B (MAO-B) through its unique ability to form ionic bonds and engage in π-π stacking with aromatic residues. This compound's distinct electronic configuration facilitates rapid electron transfer, influencing the enzyme's catalytic efficiency. Its crystalline structure enhances stability, while the dihydrate form contributes to solubility, allowing for effective diffusion in biological systems. | ||||||
trans 2-Phenylcyclopropylamine Hydrochloride | 1986-47-6 | sc-208452 sc-208452A | 250 mg 1 g | $56.00 $163.00 | 1 | |
Trans 2-Phenylcyclopropylamine Hydrochloride exhibits intriguing interactions with monoamine oxidase B (MAO-B) by forming hydrogen bonds and engaging in hydrophobic interactions with the enzyme's active site. Its cyclopropyl moiety introduces strain, enhancing binding affinity and altering reaction kinetics. The compound's unique stereochemistry allows for selective inhibition, while its hydrochloride form improves solubility, promoting effective interaction dynamics within biochemical pathways. | ||||||
R(−)-Deprenyl hydrochloride | 14611-52-0 | sc-200742 sc-200742A sc-200742B | 100 mg 250 mg 1 g | $32.00 $77.00 $281.00 | ||
R(-)-Deprenyl hydrochloride acts as a selective inhibitor of monoamine oxidase B (MAO-B), showcasing unique binding characteristics due to its asymmetric structure. The compound's hydrophobic regions facilitate strong interactions with the enzyme, while its specific stereochemistry enhances its affinity for the active site. This selective inhibition alters the enzymatic reaction kinetics, allowing for a nuanced modulation of neurotransmitter metabolism, which can influence various biochemical processes. | ||||||
cis-Resveratrol | 61434-67-1 | sc-363863 sc-363863A | 10 mg 100 mg | $340.00 $2400.00 | 2 | |
Cis-Resveratrol exhibits intriguing interactions with monoamine oxidase B (MAO-B) through its polyphenolic structure, which allows for multiple hydrogen bonding and π-π stacking with the enzyme's active site. This compound's unique conformation promotes selective binding, influencing the enzyme's catalytic efficiency. Additionally, its antioxidant properties may modulate oxidative stress pathways, further impacting MAO-B activity and related metabolic processes. | ||||||
Ro 16-6491 | 94319-79-6 | sc-200743 sc-200743A | 200 mg 1 g | $57.00 $218.00 | ||
Ro 16-6491 demonstrates a distinctive affinity for monoamine oxidase B (MAO-B) through its unique structural features, which facilitate specific hydrophobic interactions and electrostatic complementarity with the enzyme's active site. This compound exhibits a notable ability to stabilize the enzyme-substrate complex, thereby altering reaction kinetics. Its conformational flexibility allows for dynamic adjustments during binding, potentially influencing the enzyme's overall activity and regulatory mechanisms. | ||||||
Pargyline hydrochloride | 306-07-0 | sc-215676 sc-215676A | 500 mg 1 g | $39.00 $82.00 | 2 | |
Pargyline hydrochloride exhibits a selective interaction with monoamine oxidase B (MAO-B), characterized by its ability to form stable hydrogen bonds and hydrophobic contacts within the enzyme's active site. This compound's unique steric configuration enhances its binding affinity, leading to a modulation of the enzyme's catalytic efficiency. Additionally, its electronic properties may influence the redox state of the enzyme, impacting the overall metabolic pathways associated with neurotransmitter degradation. | ||||||