MAO-B Inhibitors
Items 11 to 20 of 25 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lazabemide hydrochloride | 103878-83-7 | sc-202208 sc-202208A | 10 mg 50 mg | $79.00 $446.00 | ||
Lazabemide hydrochloride selectively inhibits monoamine oxidase B (MAO-B) through specific interactions that stabilize the enzyme's conformation. Its unique structural features allow for effective steric hindrance, which disrupts substrate access to the active site. The compound's electron-donating characteristics may alter the enzyme's redox potential, thereby influencing the kinetics of neurotransmitter metabolism. This modulation can lead to distinct effects on enzymatic activity and metabolic regulation. | ||||||
N-Methyl-N-propargylbenzylamine | 555-57-7 | sc-236062 | 5 g | $67.00 | ||
N-Methyl-N-propargylbenzylamine, an older MAO-B inhibitor, operates by inhibiting the enzyme's activity. | ||||||
8-(3-Chlorostyryl)caffeine | 147700-11-6 | sc-203786 sc-203786A | 10 mg 50 mg | $209.00 $362.00 | 7 | |
8-(3-Chlorostyryl)caffeine exhibits selective inhibition of monoamine oxidase B (MAO-B) through unique molecular interactions that enhance binding affinity. Its chlorostyryl group introduces steric bulk, effectively blocking substrate entry and altering the enzyme's active site dynamics. The compound's electron-withdrawing properties may influence the enzyme's catalytic efficiency, impacting the overall reaction kinetics and metabolic pathways associated with neurotransmitter degradation. | ||||||
Rasagiline Mesylate | 161735-79-1 | sc-206071 sc-206071A | 25 mg 100 mg | $165.00 $290.00 | ||
Rasagiline Mesylate functions as a selective inhibitor of monoamine oxidase B (MAO-B) by engaging in specific molecular interactions that stabilize its binding to the enzyme. The presence of the mesylate group enhances solubility and facilitates unique conformational changes in the enzyme, which may alter substrate accessibility. This compound's kinetic profile suggests a slow, sustained inhibition, potentially affecting the enzyme's turnover rate and influencing metabolic flux in related biochemical pathways. | ||||||
Mofegiline hydrochloride | 120635-25-8 | sc-269606 sc-269606A | 250 mg 1 g | $1300.00 $2889.00 | ||
Mofegiline hydrochloride acts as a selective MAO-B inhibitor, characterized by its unique ability to form stable interactions with the enzyme's active site. The hydrochloride moiety enhances its solubility, promoting effective diffusion in biological systems. Its kinetic behavior indicates a competitive inhibition mechanism, where it modulates the enzyme's affinity for substrates, potentially leading to altered metabolic dynamics. This compound's structural features may also influence enzyme conformational states, impacting overall activity. | ||||||
rac Rasagiline-13C3 Mesylate | sc-219877 | 1 mg | $430.00 | |||
Rasagiline-13C3 Mesylate is a selective MAO-B inhibitor that exhibits unique isotopic labeling, allowing for detailed metabolic tracking in biochemical studies. Its mesylate group enhances solubility and stability, facilitating interactions with the enzyme's active site. The compound demonstrates distinct reaction kinetics, characterized by a non-linear inhibition profile that may influence substrate turnover rates. Additionally, its molecular structure may induce specific conformational changes in the enzyme, affecting catalytic efficiency. | ||||||
1-Hydrazinophthalazine Hydrochloride | 304-20-1 | sc-206167 | 10 g | $280.00 | ||
1-Hydrazinophthalazine Hydrochloride acts as a selective MAO-B inhibitor, showcasing unique molecular interactions that enhance its binding affinity to the enzyme. Its hydrazine moiety facilitates hydrogen bonding, promoting stability within the active site. The compound's distinct electronic properties may influence electron transfer mechanisms, altering reaction kinetics. Furthermore, its structural conformation can induce specific allosteric effects, potentially modulating enzyme activity and substrate accessibility. | ||||||
Safinamide mesylate | 202825-46-5 | sc-364754 sc-364754A | 5 mg 25 mg | $88.00 $273.00 | ||
Safinamide mesylate functions as a selective MAO-B inhibitor, characterized by its unique structural features that enhance enzyme interaction. The presence of a mesylate group contributes to its solubility and stability, while the compound's rigid framework allows for optimal spatial orientation within the active site. This configuration may facilitate specific electrostatic interactions, influencing the enzyme's conformational dynamics and modulating substrate binding efficiency. | ||||||
1,2-benzoxazol-3-ylmethanesulfonamide | 68291-97-4 | sc-339184 sc-339184A | 250 mg 1 g | $162.00 $331.00 | ||
1,2-benzoxazol-3-ylmethanesulfonamide exhibits selective inhibition of MAO-B through its distinctive benzoxazole moiety, which enhances π-π stacking interactions with aromatic residues in the enzyme's active site. The sulfonamide group promotes hydrogen bonding, stabilizing the enzyme-inhibitor complex. Its unique electronic properties may influence reaction kinetics, potentially altering the enzyme's catalytic efficiency and substrate specificity, thereby impacting metabolic pathways. | ||||||
4-Oxo-4H-1-benzopyran-2-carboxylic acid | 4940-39-0 | sc-238937 | 5 g | $39.00 | ||
4-Oxo-4H-1-benzopyran-2-carboxylic acid acts as a selective MAO-B inhibitor, characterized by its unique chromone structure that facilitates strong hydrophobic interactions within the enzyme's active site. The carboxylic acid group enhances solubility and promotes ionic interactions, which may modulate the enzyme's conformational dynamics. This compound's distinct electronic configuration can influence binding affinity and alter the enzyme's overall activity, affecting metabolic processes. | ||||||