Mammaglobin B Inhibitors
Mammaglobin B Inhibitors as a chemical class refers to compounds that interfere with the function or regulation of the Mammaglobin B protein. This interference can occur through various mechanisms, such as modulation of signaling pathways that control the protein's expression, post-translational modifications, or its stability within the cellular environment. The chemicals listed above act on distinct cellular targets and pathways, which in turn can alter the intracellular milieu and affect the behavior and levels of a wide array of proteins, including Mammaglobin B, despite the primary targets of these chemicals not being the protein itself.
The inhibitors listed, such as staurosporine and LY294002, target protein kinases and PI3K, respectively, which are enzymes involved in the transmission of signals that regulate cellular functions including gene expression. Disruption of these enzymes can lead to altered protein expression profiles within the cell, including that of Mammaglobin B. Similarly, MEK inhibitors like U0126 and PD98059, the p38 MAPK inhibitor SB203580, and the JNK inhibitor SP600125, can influence signaling pathways that are crucial for the regulation of gene expression, which may affect the synthesis and function of Mammaglobin B. The PI3K/Akt pathway, targeted by both LY294002 and wortmannin, is involved in many cellular processes including cell survival, proliferation, and protein synthesis, thus affecting proteins regulated by this pathway.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A kinase inhibitor that inhibits a wide range of protein kinases, which can alter signaling pathways that control the expression and function of proteins, including Mammaglobin B. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that blocks the PI3K/Akt pathway, a signaling route that can regulate the expression of genes and proteins, potentially including Mammaglobin B. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Another MEK inhibitor that can block the MAPK/ERK pathway, affecting the regulation of protein expression and function, including that of Mammaglobin B. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can modulate inflammatory responses and other signaling cascades that may control the expression of proteins like Mammaglobin B. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK that can affect signaling pathways involved in the regulation of gene expression and protein stability, potentially influencing Mammaglobin B. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can also affect the PI3K/Akt pathway, altering the expression and function of a variety of proteins, possibly including Mammaglobin B. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can affect cell growth and proliferation signaling pathways, potentially impacting the regulation of Mammaglobin B expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A glucocorticoid receptor agonist that can modulate gene expression, and in turn could influence the expression levels of proteins such as Mammaglobin B. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can inhibit calcineurin, affecting the NFAT signaling pathway, which may control the expression of proteins including Mammaglobin B. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can change chromatin structure and gene expression, possibly affecting Mammaglobin B expression. | ||||||