Date published: 2026-4-1

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MAGE-D4 Activators

MAGE-D4, short for Melanoma Antigen Gene-D4, is a member of the MAGE (Melanoma Antigen) protein family. These proteins are known for their involvement in various cellular processes, and they have garnered attention due to their association with cancer, particularly melanoma. MAGE-D4, like other MAGE proteins, has been identified as a potential regulator of cell growth and differentiation, although its precise functions in normal cellular processes are still being elucidated. Activators of MAGE-D4 are compounds or molecules that enhance the protein's activity or modulate its function within cells.

MAGE-D4 activators may work through different mechanisms to influence the protein's role in cellular physiology. They can potentially affect protein-protein interactions, post-translational modifications, or subcellular localization of MAGE-D4. Understanding these activators can provide insights into the broader regulatory networks in which MAGE-D4 participates and its potential contributions to normal cellular functions. Moreover, investigating MAGE-D4 activators may shed light on its potential roles in various developmental and physiological contexts beyond cancer biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

This demethylating agent could potentially induce MAGE-D4 expression by reversing methylation silencing of gene expression.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

As a histone deacetylase inhibitor, Trichostatin A can activate transcription by changing chromatin structure, possibly affecting MAGE-D4.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate acts as a histone deacetylase inhibitor, which could lead to the induction of MAGE-D4 expression through epigenetic modification.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid influences differentiation and may upregulate cancer/testis antigens like MAGE-D4 in certain cell types.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

This glucocorticoid affects gene expression and could potentially modulate MAGE-D4 levels.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D3 has regulatory roles in gene expression and could potentially influence the expression of MAGE-D4.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin raises intracellular cAMP, which might lead to changes in gene expression, including MAGE-D4.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG affects multiple signaling pathways and may modulate the expression of genes like MAGE-D4.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane affects transcription factors and might induce MAGE-D4 expression as part of stress response pathways.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$53.00
$89.00
7
(1)

Known to modify copper metabolism in the cell, disulfiram can influence gene expression and potentially induce MAGE-D4.