MAGE-D4, short for Melanoma Antigen Gene-D4, is a member of the MAGE (Melanoma Antigen) protein family. These proteins are known for their involvement in various cellular processes, and they have garnered attention due to their association with cancer, particularly melanoma. MAGE-D4, like other MAGE proteins, has been identified as a potential regulator of cell growth and differentiation, although its precise functions in normal cellular processes are still being elucidated. Activators of MAGE-D4 are compounds or molecules that enhance the protein's activity or modulate its function within cells.
MAGE-D4 activators may work through different mechanisms to influence the protein's role in cellular physiology. They can potentially affect protein-protein interactions, post-translational modifications, or subcellular localization of MAGE-D4. Understanding these activators can provide insights into the broader regulatory networks in which MAGE-D4 participates and its potential contributions to normal cellular functions. Moreover, investigating MAGE-D4 activators may shed light on its potential roles in various developmental and physiological contexts beyond cancer biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This demethylating agent could potentially induce MAGE-D4 expression by reversing methylation silencing of gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, Trichostatin A can activate transcription by changing chromatin structure, possibly affecting MAGE-D4. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate acts as a histone deacetylase inhibitor, which could lead to the induction of MAGE-D4 expression through epigenetic modification. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences differentiation and may upregulate cancer/testis antigens like MAGE-D4 in certain cell types. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
This glucocorticoid affects gene expression and could potentially modulate MAGE-D4 levels. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 has regulatory roles in gene expression and could potentially influence the expression of MAGE-D4. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin raises intracellular cAMP, which might lead to changes in gene expression, including MAGE-D4. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG affects multiple signaling pathways and may modulate the expression of genes like MAGE-D4. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane affects transcription factors and might induce MAGE-D4 expression as part of stress response pathways. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Known to modify copper metabolism in the cell, disulfiram can influence gene expression and potentially induce MAGE-D4. | ||||||