LUC7L2 Activators
LUC7-like 2 (LUC7L2) is a protein encoded by the LUC7L2 gene, which is conserved across several species, indicating its importance in cellular processes. This protein is involved in the complex machinery of RNA splicing, a critical step in the post-transcriptional modification of RNA transcripts where non-coding regions (introns) are removed and coding regions (exons) are joined together. LUC7L2 is associated with the spliceosome, a large ribonucleoprotein complex that orchestrates the splicing of pre-messenger RNA (pre-mRNA) into mature mRNA.
The precise function of LUC7L2 is not fully delineated, but it is thought to play a role in the regulation of alternative splicing, a process that allows a single gene to produce multiple protein isoforms, thereby contributing to proteomic diversity and the regulation of gene expression. Alternative splicing is a fundamental mechanism for the development, differentiation, and response to environmental stimuli in eukaryotic organisms.Mutations or dysregulation of splicing factors, including LUC7L2, can lead to aberrant splicing events, which are implicated in various diseases, including cancer and genetic disorders. The expression of LUC7L2 may be influenced by cellular stress, developmental stage, and tissue type, reflecting its involvement in the fine-tuning of gene expression in response to physiological demands.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
May regulate gene expression by activating nuclear receptors that bind to DNA response elements. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases cAMP, potentially influencing transcription factors and gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can lead to chromatin remodeling and affect gene transcription. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferases, potentially causing gene demethylation and activation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Histone deacetylase inhibitor that can affect gene expression by altering chromatin structure. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
May modulate gene expression through epigenetic changes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid that can regulate gene expression by acting on glucocorticoid response elements. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
May impact gene expression through pathways such as GSK-3 modulation. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Binds to estrogen receptors, potentially affecting gene transcription in a tissue-specific manner. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C, which can lead to changes in transcription factor activities. | ||||||