LSDP5 inhibitors belong to a class of chemical compounds designed to selectively target and modulate the activity of the Liver-Specific Protein 5, abbreviated as LSDP5. LSDP5, also known as PIG3 (P53-induced gene 3), is a protein that is predominantly expressed in the liver and belongs to the PIG family of proteins. The exact function of LSDP5 is still the subject of ongoing research, and its precise role in cellular processes remains to be fully elucidated. However, it has been associated with p53-mediated responses to cellular stress and DNA damage, suggesting its involvement in cell cycle regulation, DNA repair, and apoptosis. LSDP5 inhibitors are developed through chemical synthesis and structural optimization techniques, with the primary goal of interacting with specific domains or functional motifs of the LSDP5 protein to influence its cellular functions.
The design of LSDP5 inhibitors typically involves creating molecules that can selectively bind to LSDP5, disrupting its interactions with other proteins or modulating its activity in response to cellular stress signals. By targeting LSDP5 activity, these inhibitors can impact cellular responses to stress and DNA damage, shedding light on the intricate molecular mechanisms underlying these critical processes. The study of LSDP5 inhibitors contributes to our understanding of basic cell biology and the regulatory networks that govern cellular responses to stress and DNA damage. This research provides valuable insights into the role of LSDP5 within the cell and its significance in cellular homeostasis and stress responses.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that incorporates into DNA and RNA, it can inhibit DNA methyltransferase, potentially altering gene expression. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
A diterpene triepoxide that can inhibit transcriptional activity by affecting transcription factors and RNA polymerase. | ||||||
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
An environmental estrogen that may disrupt endocrine function and alter gene expression patterns in cells. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis by interfering with translational elongation, potentially reducing protein levels. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
A cyclin-dependent kinase inhibitor that can halt cell cycle progression and influence transcriptional regulation. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $68.00 $261.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, potentially affecting nucleotide synthesis and gene expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Binds to mTOR and inhibits its pathway, which can lead to changes in protein synthesis and gene expression. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
A compound in cruciferous vegetables that may affect gene expression through its influence on antioxidant response elements. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A phosphoinositide 3-kinase inhibitor, which can alter cellular signaling and potentially affect gene expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which plays a role in cell signaling and can impact gene expression. |