The chemical class of LRRN2 inhibitors encompasses a range of compounds designed to modulate the activity of the LRRN2 protein, which is characterized by leucine-rich repeats and is involved in important neuronal processes. These inhibitors target various aspects of LRRN2's function, focusing primarily on its role in neuronal signaling, development, and cytoskeletal dynamics. The aim of these inhibitors is to influence the interaction of LRRN2 with other cellular components and signaling pathways, thereby affecting its functional activity within neuronal cells. The inhibition mechanisms can vary, including disruption of protein-protein interactions, alteration of cytoskeletal organization, and modulation of signaling pathways where LRRN2 plays a role.
The significance of these inhibitors lies in their ability to target specific functions of LRRN2. By affecting the protein's role in neuronal development and signaling, these compounds can impact processes such as neurite outgrowth, synaptic function, and neuronal response to external stimuli. Additionally, by influencing signaling pathways, these inhibitors can impact processes like cell growth and differentiation. The diversity in the mechanisms of action of LRRN2 inhibitors underscores the complexity of the protein's role in neuronal processes. Their targeted approach allows for the modulation of LRRN2 activity in a nuanced manner, which is particularly important in the context of the intricate networks and functions in which LRRN2 is involved. As research continues to deepen our understanding of LRRN2's function and its interactions within the cell, the development and refinement of these inhibitors are expected to evolve, offering more precise methods to influence this protein's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An MEK inhibitor; could possibly inhibit LRRN2 by influencing MAPK/ERK signaling pathways, affecting neuronal signaling and development. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Targets p38 MAP kinase; could possibly inhibit LRRN2 by impacting stress response signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K; could possibly inhibit LRRN2 by affecting signaling pathways associated with cell survival and proliferation. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Disrupts microtubule polymerization; could possibly inhibit LRRN2's role in neuronal development by affecting cytoskeletal dynamics. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor; could possibly inhibit LRRN2 by altering cytoskeletal dynamics, affecting its interaction with the cytoskeleton. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor; could possibly inhibit LRRN2 by altering cell signaling pathways. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
Inhibits myosin II; could possibly inhibit LRRN2 by affecting cellular motility and morphology, impacting neuronal development. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 5 g 100 g 250 g 1 kg 5 kg | $32.00 $66.00 $95.00 $188.00 $760.00 | 13 | |
Affects multiple signaling pathways; could possibly inhibit LRRN2's role in cellular signaling and neuronal response mechanisms. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A broad-spectrum kinase inhibitor; could possibly inhibit LRRN2 by affecting various signaling pathways where it is involved. | ||||||