The chemical class of LRCH2 Inhibitors constitutes a specialized group of compounds designed to modulate the activity of the LRCH2 protein. This class of inhibitors targets the protein's involvement in various cellular processes, primarily focusing on its role in cytoskeletal dynamics and cell signaling pathways. By intervening in these processes, the inhibitors can alter the functional activity of LRCH2, which is characterized by its leucine-rich repeats and calponin homology domain. These inhibitors are tailored to affect the interaction of LRCH2 with other cellular components, particularly those involved in the cytoskeleton and signaling molecules. The inhibition can occur through various mechanisms, including the disruption of protein-protein interactions, alteration of cytoskeletal organization, and modulation of signaling pathways where LRCH2 plays a role.
The significance of these inhibitors lies in their ability to target specific cellular functions of LRCH2. By influencing the protein's interaction with the cytoskeleton, these inhibitors can affect cell shape, motility, and intracellular transport, all of which are crucial for normal cellular functioning and response to external stimuli. Additionally, by modulating cell signaling pathways, these inhibitors can impact processes such as cell growth, differentiation, and immune responses. The diversity in the mechanisms of action of LRCH2 inhibitors underscores the complexity of the protein's role in cellular processes. Their targeted approach allows for the modulation of LRCH2 activity without disrupting essential cellular functions. This specificity is particularly important in the context of complex signaling networks and cytoskeletal dynamics where LRCH2 is involved. As research continues to unfold the intricacies of LRCH2's function and its interactions within the cell, the development and refinement of these inhibitors are expected to advance, offering more nuanced ways to influence this protein's activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A Rho-associated protein kinase (ROCK) inhibitor; could possibly inhibit LRCH2 by altering cytoskeletal dynamics and its interaction with the cytoskeleton. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin polymerization; could possibly inhibit LRCH2's role in cytoskeletal organization and actin-binding interactions. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MEK inhibitor; could possibly inhibit LRCH2 by affecting MAPK/ERK signaling pathways. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Inhibits p38 MAP kinase; could possibly inhibit LRCH2 by impacting stress response signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor; could possibly inhibit LRCH2 by influencing signaling pathways associated with cell survival and proliferation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor; could possibly inhibit LRCH2 by altering cell signaling pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Affects multiple signaling pathways; could possibly inhibit LRCH2's role in cellular signaling and response mechanisms. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Disrupts microtubule polymerization; could possibly inhibit LRCH2's involvement in cellular processes and cytoskeletal interactions. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II; could possibly inhibit LRCH2 by affecting cellular motility and morphology. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad-spectrum kinase inhibitor; could possibly inhibit LRCH2 by affecting various signaling pathways. | ||||||