Date published: 2026-2-14

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LRCH2 Inhibitors

The chemical class of LRCH2 Inhibitors constitutes a specialized group of compounds designed to modulate the activity of the LRCH2 protein. This class of inhibitors targets the protein's involvement in various cellular processes, primarily focusing on its role in cytoskeletal dynamics and cell signaling pathways. By intervening in these processes, the inhibitors can alter the functional activity of LRCH2, which is characterized by its leucine-rich repeats and calponin homology domain. These inhibitors are tailored to affect the interaction of LRCH2 with other cellular components, particularly those involved in the cytoskeleton and signaling molecules. The inhibition can occur through various mechanisms, including the disruption of protein-protein interactions, alteration of cytoskeletal organization, and modulation of signaling pathways where LRCH2 plays a role.

The significance of these inhibitors lies in their ability to target specific cellular functions of LRCH2. By influencing the protein's interaction with the cytoskeleton, these inhibitors can affect cell shape, motility, and intracellular transport, all of which are crucial for normal cellular functioning and response to external stimuli. Additionally, by modulating cell signaling pathways, these inhibitors can impact processes such as cell growth, differentiation, and immune responses. The diversity in the mechanisms of action of LRCH2 inhibitors underscores the complexity of the protein's role in cellular processes. Their targeted approach allows for the modulation of LRCH2 activity without disrupting essential cellular functions. This specificity is particularly important in the context of complex signaling networks and cytoskeletal dynamics where LRCH2 is involved. As research continues to unfold the intricacies of LRCH2's function and its interactions within the cell, the development and refinement of these inhibitors are expected to advance, offering more nuanced ways to influence this protein's activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

A Rho-associated protein kinase (ROCK) inhibitor; could possibly inhibit LRCH2 by altering cytoskeletal dynamics and its interaction with the cytoskeleton.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$165.00
$486.00
64
(4)

Disrupts actin polymerization; could possibly inhibit LRCH2's role in cytoskeletal organization and actin-binding interactions.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

An MEK inhibitor; could possibly inhibit LRCH2 by affecting MAPK/ERK signaling pathways.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase; could possibly inhibit LRCH2 by impacting stress response signaling pathways.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor; could possibly inhibit LRCH2 by influencing signaling pathways associated with cell survival and proliferation.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

A PI3K inhibitor; could possibly inhibit LRCH2 by altering cell signaling pathways.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

Affects multiple signaling pathways; could possibly inhibit LRCH2's role in cellular signaling and response mechanisms.

Colchicine

64-86-8sc-203005
sc-203005A
sc-203005B
sc-203005C
sc-203005D
sc-203005E
1 g
5 g
50 g
100 g
500 g
1 kg
$100.00
$321.00
$2289.00
$4484.00
$18207.00
$34749.00
3
(2)

Disrupts microtubule polymerization; could possibly inhibit LRCH2's involvement in cellular processes and cytoskeletal interactions.

(S)-(−)-Blebbistatin

856925-71-8sc-204253
sc-204253A
sc-204253B
sc-204253C
1 mg
5 mg
10 mg
25 mg
$72.00
$265.00
$495.00
$968.00
(2)

Inhibits myosin II; could possibly inhibit LRCH2 by affecting cellular motility and morphology.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

A broad-spectrum kinase inhibitor; could possibly inhibit LRCH2 by affecting various signaling pathways.