LOXL4 Activators
LOXL4 Activators, as defined in this context, are a class of compounds that can indirectly influence the activity of LOXL4. These activators function primarily by providing essential cofactors, modulating gene expression, or altering cellular environments that are conducive to LOXL4's enzymatic activity. Cofactors like Copper Sulfate and Manganese Chloride are critical for LOXL4's catalytic function, and their presence can enhance the enzyme's activity. Antioxidants such as Ascorbic Acid, Hydrogen Peroxide, N-Acetylcysteine, and Taurine can indirectly influence LOXL4 by maintaining an optimal oxidative environment necessary for its activity. In contrast, compounds like β-Aminopropionitrile and D-Penicillamine, known for their interactions with lysyl oxidases, might modulate LOXL4 activity indirectly under specific conditions.
Furthermore, compounds influencing gene expression and cellular signaling, such as Retinoic Acid, EGCG, Curcumin, and Resveratrol, can potentially affect LOXL4 indirectly. These compounds may influence the expression levels of LOXL4 or the availability of its substrates by modulating related pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Copper is a cofactor for LOXL4, and copper sulfate can act as an indirect activator by providing the necessary copper ions for its enzymatic activity. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Ascorbic Acid is essential for collagen synthesis and may indirectly enhance LOXL4 activity by promoting substrate availability. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid can influence gene expression and cellular differentiation, potentially affecting LOXL4 expression indirectly. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $30.00 | ||
Manganese is another cofactor for lysyl oxidases, and its chloride salt can provide manganese ions to indirectly support LOXL4 activity. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Hydrogen Peroxide may be involved in oxidative processes related to LOXL4's catalytic mechanism, potentially influencing its activity indirectly. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can influence various signaling pathways and might indirectly affect LOXL4 activity through antioxidant mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can modulate cellular signaling and oxidative stress, potentially influencing LOXL4 activity indirectly. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can affect gene expression and cellular signaling pathways, potentially influencing LOXL4 activity. | ||||||
Penicillamine | 52-67-5 | sc-205795 sc-205795A | 1 g 5 g | $45.00 $94.00 | ||
D-Penicillamine binds copper and can modulate copper availability for LOXL4, potentially affecting its activity. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
Taurine has antioxidant properties and can influence cellular redox states, potentially impacting LOXL4 activity. | ||||||