Date published: 2026-4-1

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LOC730060 Inhibitors

Triciribine and Dasatinib, for instance, target AKT and Src family kinases, respectively, both of which are critical components of cell signaling and could affect LOC730060 if it is a part of these pathways. GO6983 and PD0325901, by inhibiting PKC and MEK, can alter the phosphorylation states and signaling cascades that might impinge upon LOC730060's function.

Roscovitine's inhibition of CDKs and SB431542's targeting of the TGF-beta receptor provide means by which cell cycle progression and growth factor signaling can be modulated, potentially affecting the role of LOC730060 in these processes. Gefitinib's action on EGFR and ZM-447439's on Aurora kinases can influence signal transduction related to cell growth and division, which may extend to the modulation of LOC730060. Y-27632, as a ROCK inhibitor, and 5-Azacytidine, by its action on DNA methyltransferases, can alter cytoskeletal dynamics and gene expression patterns, respectively, thereby possibly influencing the cellular context within which LOC730060 operates. Alsterpaullone's inhibition of GSK-3beta can affect the Wnt signaling pathway, while 4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibition of NF-kB signaling can alter transcriptional regulation, both of which are processes that could potentially modulate the activity or expression of LOC730060.

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triciribine

35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$104.00
$141.00
14
(1)

Inhibits AKT, which may affect LOC730060 if it is a downstream target of AKT signaling.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

A Src family kinase inhibitor that may alter signaling cascades involving LOC730060.

Gö 6983

133053-19-7sc-203432
sc-203432A
sc-203432B
1 mg
5 mg
10 mg
$105.00
$299.00
$474.00
15
(1)

Inhibits protein kinase C, possibly affecting LOC730060 if it is regulated by PKC-mediated phosphorylation.

Roscovitine

186692-46-6sc-24002
sc-24002A
1 mg
5 mg
$94.00
$265.00
42
(2)

Inhibits cyclin-dependent kinases (CDKs), potentially altering cell cycle-related processes involving LOC730060.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

Inhibits the TGF-beta receptor, potentially impacting LOC730060 if it is involved in TGF-beta signaling.

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

Inhibits EGFR tyrosine kinase, which may affect LOC730060 activity if it is downstream of EGFR signaling.

ZM-447439

331771-20-1sc-200696
sc-200696A
1 mg
10 mg
$153.00
$356.00
15
(1)

Aurora kinase inhibitor, may alter cell division processes that could involve LOC730060.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

Inhibits ROCK, potentially affecting cytoskeletal dynamics and related signaling implicating LOC730060.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Inhibits DNA methyltransferases, potentially affecting gene expression patterns including those of LOC730060.

Alsterpaullone

237430-03-4sc-202453
sc-202453A
1 mg
5 mg
$68.00
$312.00
2
(1)

Inhibits GSK-3beta, possibly impacting Wnt signaling pathway and subsequently LOC730060.