Kinase inhibitors such as Staurosporine, LY294002, and Sorafenib target various kinases that relay signals controlling cell growth, survival, and proliferation. By inhibiting these kinases, the inhibitors can alter signaling cascades that LOC729829 may be a part of. Inhibitors like SB203580, SP600125, and PD98059 act on MAPK pathway components, which are central to the regulation of cell responses to a variety of stimuli. These molecules' inhibition of specific MAPKs can impact cellular responses that LOC729829 is potentially associated with.
MG132's effects on the ubiquitin-proteasome system can lead to altered protein turnover, potentially impacting LOC729829 stability. BAY 11-7082's action on the NF-κB pathway can influence gene transcription and cell survival signals, possibly affecting LOC729829's regulatory roles. Roscovitine and ZM-447439, by targeting cell cycle kinases and Aurora kinases respectively, can disrupt cell division mechanisms, which may be processes where LOC729829 is involved. Angiogenesis inhibitors like 2-Methoxyestradiol can affect cell growth and division by targeting microtubules, potentially impacting cellular functions where LOC729829 plays a part. Lastly, Niclosamide's inhibition of the Wnt/β-catenin pathway can affect gene transcription and cellular signaling pathways, potentially involving LOC729829 in their broad regulatory roles.
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Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A kinase inhibitor that can inhibit a wide range of protein kinases potentially involved in the same pathways as LOC729829. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can disrupt the PI3K/Akt pathway, which may affect the activity of LOC729829 if it is part of this signaling cascade. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can block the p38 signaling pathway, potentially affecting inflammatory response processes involving LOC729829. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
An angiogenesis inhibitor that can disrupt microtubule function, potentially influencing cell division and LOC729829 if it is involved in cell cycle regulation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK) that can alter transcription factor activity, potentially affecting LOC729829 if it is regulated by JNK signaling. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
An Aurora kinase inhibitor that can disrupt cell division, possibly affecting LOC729829 if it plays a role in mitosis. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
An ERK inhibitor that can prevent the activation of the MAPK/ERK pathway, potentially affecting cell growth or differentiation processes involving LOC729829. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
A cyclin-dependent kinase inhibitor that can halt the cell cycle, potentially affecting LOC729829 if it is involved in cell cycle control. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
A Raf kinase inhibitor that can block the Raf/MEK/ERK pathway, potentially affecting cell proliferation and survival where LOC729829 might be involved. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
An NF-κB pathway inhibitor that can alter the transcription of genes involved in inflammation and cell survival, potentially affecting LOC729829 function. | ||||||