LOC729791 Inhibitors
Inhibitors that act on kinase activity, such as Triciribine, can suppress the Akt pathway, thereby influencing cell survival mechanisms that LOC729791 might control. Erlotinib and Sorafenib offer different modes of action by targeting EGFR and multiple kinases, respectively, thus potentially affecting cell proliferation and signal transduction processes. Compounds like ZM-447439 and Bortezomib provide a means to interfere with cell cycle progression and protein degradation pathways, which could be essential for the proper functioning of LOC729791 within the cell. Thapsigargin, through its action on SERCA, may disrupt intracellular calcium signaling, a pathway that LOC729791 could be a part of. LY294002's inhibition of PI3K and PD173074's targeting of FGFR tyrosine kinase represent interventions in growth factor signaling and cellular differentiation, potentially intersecting with LOC729791's role.
Y-27632 influences cell shape and motility by inhibiting ROCK kinase, which could also be related to the function of LOC729791. The influence of 5-Azacytidine on gene expression through DNA methyltransferase inhibition may alter the epigenetic landscape in which LOC729791 operates. 2-Methoxyestradiol's effect on microtubule stability could impact cell division and intracellular transport processes that involve LOC729791. Lastly, the unique action of Omecamtiv mecarbil on myosin ATPase activity might affect cellular contractility systems where LOC729791 plays a part.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Inhibits Akt signaling, potentially altering cell survival and metabolism that might be regulated by LOC729791. | ||||||
Erlotinib, Free Base | 183321-74-6 | sc-396113 sc-396113A sc-396113B sc-396113C sc-396113D | 500 mg 1 g 5 g 10 g 100 g | $85.00 $132.00 $287.00 $495.00 $3752.00 | 42 | |
Inhibits EGFR tyrosine kinase activity, possibly affecting growth signal transduction pathways involving LOC729791. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $56.00 $260.00 $416.00 | 129 | |
Inhibits multiple kinases, potentially impacting pathways that control cell proliferation and angiogenesis linked to LOC729791. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Inhibits Aurora kinase activity, possibly affecting cell cycle progression and mitosis that may involve LOC729791. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Inhibits the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), potentially disrupting calcium signaling linked to LOC729791. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, potentially downregulating downstream signaling pathways including those linked to LOC729791. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
Inhibits FGFR tyrosine kinase, which can impact cell growth and differentiation pathways associated with LOC729791. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK kinase, potentially influencing cytoskeleton organization and cell motility related to LOC729791. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Inhibits proteasome activity, potentially altering protein degradation pathways in which LOC729791 may be involved. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferase, potentially affecting gene expression and epigenetic regulation linked to LOC729791. | ||||||