LOC729181 Activators
LOC729181 Activators represent a set of chemical compounds that, through various cellular signaling pathways and processes, enhance the functional activity of LOC729181. Phorbol 12-myristate 13-acetate (PMA) activates Protein kinase C (PKC), which can directly phosphorylate LOC729181 or proteins within its signaling network, enhancing LOC729181 activity. Similarly, Calmodulin inhibitors like W-7 disrupt calcium signaling, which could lead to the activation of alternative pathways that indirectly enhance LOC729181 activity if LOC729181 is influenced by calcium-dependent mechanisms.
Calcium ionophores such as A23187 directly increase intracellular calcium levels, potentially activating calcium-dependent proteins and pathways that could enhance LOC729181 activity. Forskolin, by increasing cAMP, can activate PKA, which may phosphorylate proteins in pathways that include LOC729181, leading to its enhanced activity. U73122 can alter phosphoinositide signaling, leading to changes in downstream signaling pathways that include LOC729181, thereby enhancing its activity. LY294002, as a PI3K inhibitor, can induce compensatory activation of pathways that might upregulate LOC729181 activity. Okadaic Acid prevents the dephosphorylation of proteins, potentially increasing LOC729181 activity if it is regulated by phosphorylation status.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Protein kinase C (PKC) activator that simulates diacylglycerol, leading to PKC translocation and activation. PKC activation enhances LOC729181 activity through phosphorylation events within signaling pathways that LOC729181 is a part of. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
Calcium ionophore that increases intracellular calcium levels, leading to activation of calcium-dependent proteins and pathways that interact with LOC729181, potentially enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor that can lead to compensatory activation of alternative pathways that enhance LOC729181 activity if it is involved in PI3K/Akt signaling. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
PP2A inhibitor that prevents the dephosphorylation of proteins, potentially increasing phosphorylation levels and enhancing LOC729181 activity if it is regulated by phosphorylation. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
CaMKII inhibitor that can lead to altered calcium signaling, potentially enhancing LOC729181 activity through feedback mechanisms if it is part of the calcium signaling pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor that may enhance LOC729181 activity through stress-activated protein kinase pathways if LOC729181 is regulated through these pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor that can lead to compensatory mechanisms in the MAPK/ERK pathway, potentially enhancing LOC729181 activity if it operates within this pathway. | ||||||
NF449 | 627034-85-9 | sc-478179 sc-478179A sc-478179B | 10 mg 25 mg 100 mg | $203.00 $469.00 $1509.00 | 1 | |
Gs-alpha subunit specific antagonist that can influence cAMP production, potentially enhancing LOC729181 activity through G-protein coupled receptor-mediated signaling if LOC729181 is regulated by this pathway. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $90.00 $317.00 | 17 | |
PKC inhibitor that can lead to compensatory activation of PKC-dependent pathways, potentially enhancing LOC729181 activity if it is downstream of or regulated by PKC signaling. | ||||||