LOC728504 Inhibitors
PI3K inhibitors like LY294002 and Wortmannin would affect the PI3K/Akt pathway, thereby influencing processes such as cell growth, survival, and metabolism that could be downstream of LOC728504's activity. Similarly, inhibitors of the MAPK pathway, such as PD98059, U0126, and SB203580, would alter the signaling cascade that regulates cell differentiation, proliferation, and death, which could be altered by LOC728504's function.
Inhibitors like Rapamycin, which target the mTOR pathway, would exert their effects on protein synthesis and cell growth, potentially intersecting with the role of LOC728504 in cell proliferation. Tyrosine kinase inhibitors such as Tyrphostin B42, PP2, Dasatinib, and Imatinib Mesylate provide broad-spectrum modulation of critical cell signaling pathways that include cell cycle progression, apoptosis, and cellular metabolism, which could be regulated in part by LOC728504. Gefitinib's inhibition of EGFR tyrosine kinase would impact cell adhesion, migration, and proliferation, providing further potential points of intersection with LOC728504-mediated processes.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A selective inhibitor of phosphoinositide 3-kinases (PI3K), which can downregulate downstream signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of mitogen-activated protein kinase kinase (MEK), which can alter MAPK pathway signaling. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A selective inhibitor of p38 MAPK, which can modulate pro-inflammatory cytokine production and cell apoptosis. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), which can affect stress response and apoptosis signaling pathways. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A selective inhibitor of both MEK1 and MEK2, which can interfere with the MAPK/ERK signaling cascade. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
A specific inhibitor of mTOR, which can lead to the downregulation of protein synthesis and cell proliferation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent PI3K inhibitor that can also affect downstream signaling pathways like Akt, affecting cell survival and growth. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
An inhibitor of Janus kinase 2 (JAK2), which can modulate JAK/STAT signaling pathways involved in cell growth. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
A selective inhibitor of Src family tyrosine kinases, which can alter various cell signaling processes. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A Src family kinase inhibitor that can also affect multiple other kinases, influencing growth signal transduction. | ||||||