LOC728222 Inhibitors
Wortmannin and U0126 can disrupt the PI3K and MAPK/ERK pathways, respectively, processes that are critical for cell survival, proliferation, and differentiation. Trichostatin A, by inhibiting histone deacetylases, can change chromatin structure and gene expression, potentially affecting the expression or function of LOC728222.
Cyclopamine and IWP-2, as inhibitors of the Hedgehog and Wnt signaling pathways, respectively, demonstrate the potential of these compounds to modify key developmental and cell fate determination processes. Thapsigargin's ability to disrupt calcium homeostasis and Rapamycin's inhibition of mTOR point to a possible role for LOC728222 in processes such as intracellular signaling, growth, and metabolism. Compounds like SB203580, which inhibits p38 MAPK, and 2-Methoxyestradiol, which targets HIF-1alpha and microtubules, suggest that LOC728222 may be implicated in the cellular response to stress, inflammation, and angiogenesis. Kenpaullone's inhibition of GSK-3β and cyclin-dependent kinases indicates a potential influence on cell cycle regulation and Wnt signaling, which could be modulated in the context of LOC728222 activity.
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, which can disrupt signaling pathways potentially regulated by LOC728222. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A MEK inhibitor, which can affect the MAPK/ERK pathway and potentially influence processes regulated by LOC728222. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, which can alter gene expression patterns and thereby affect LOC728222's function or expression. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
Inhibits the Hedgehog signaling pathway, which can modify developmental processes LOC728222 may be involved in. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
Inhibits Wnt production, which can alter Wnt signaling and potentially affect LOC728222's role in cellular processes. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor, which can disrupt calcium homeostasis and potentially influence LOC728222's activity or stability. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibits mTOR, which can interfere with cellular growth and proliferation processes involving LOC728222. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, which can modulate inflammatory and stress response pathways potentially involving LOC728222. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
Inhibits HIF-1alpha and microtubule dynamics, which can affect angiogenesis and cellular respiration processes involving LOC728222. | ||||||
Kenpaullone | 142273-20-9 | sc-200643 sc-200643A sc-200643B sc-200643C | 1 mg 5 mg 10 mg 25 mg | $60.00 $150.00 $226.00 $495.00 | 1 | |
Inhibits GSK-3β and CDKs, which can modulate cell cycle and Wnt signaling pathways potentially associated with LOC728222. | ||||||