LOC727845 Inhibitors
Kinase inhibitors Imatinib and Wortmannin engage with signaling proteins, possibly altering the phosphorylation landscape, which in turn can impact the activity of LOC727845. Histone deacetylase inhibitors, such as Trichostatin A and Sodium Butyrate, reshape the chromatin architecture, leading to changes in gene expression profiles that could affect the synthesis of LOC727845. MG132, by inhibiting the proteasome, prevents the degradation of proteins, potentially stabilizing LOC727845 if it is usually marked for degradation. Thapsigargin, through its disruption of calcium homeostasis, can initiate a series of events that might influence LOC727845's function, considering the widespread impact of calcium signaling in the cell.
The adenylate cyclase activator Forskolin, which raises intracellular cAMP, and the pan-caspase inhibitor Z-VAD-FMK, which inhibits apoptosis, represent molecules that modify the internal cellular state, potentially altering the activity of LOC727845. The MEK inhibitor PD98059, PI3K inhibitor LY294002, JNK inhibitor SP600125, and CaMKII inhibitor KN-93, each target specific signaling pathways, suggesting that if LOC727845 is a participant in these pathways, its activity could be influenced by these inhibitors.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
A tyrosine kinase inhibitor that can affect signaling pathways and may alter the phosphorylation state or activity of LOC727845 if it is tyrosine kinase-related. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can change chromatin structure and gene expression, possibly affecting LOC727845 expression. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
A proteasome inhibitor that can prevent the degradation of proteins, potentially increasing the levels of LOC727845 if it is normally degraded by the proteasome. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
A SERCA pump inhibitor that disrupts calcium homeostasis, which can modify signaling pathways or cellular processes related to LOC727845. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
An inhibitor of PI3K, altering signaling pathways, which can influence the activity or stability of LOC727845. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A histone deacetylase inhibitor that can lead to changes in gene expression, potentially affecting LOC727845 levels. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
A pan-caspase inhibitor that can prevent apoptosis, potentially altering the levels or activity of LOC727845 if it is related to the apoptotic process. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A specific inhibitor of MEK, which can disrupt the MAPK/ERK signaling pathway and potentially influence LOC727845 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Inhibits PI3K, which can affect the AKT signaling pathway and potentially alter the activity of LOC727845. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, modulating stress-activated protein kinase signaling, which can influence LOC727845 if it is stress-regulated. | ||||||