LOC653550 Inhibitors
Compounds like Wortmannin and U0126 can inhibit key signaling enzymes PI3K and MEK1/2, respectively, which can alter the activity of pathways that may be critical for the function of LOC653550. Trichostatin A, by inhibiting histone deacetylases, can change gene expression patterns, potentially affecting the transcriptional regulation of LOC653550. Rapamycin and Thapsigargin target fundamental cellular processes such as mTOR signaling and calcium homeostasis, which may indirectly influence the activity of LOC653550.
Imatinib and Cyclopamine, through their inhibition of specific tyrosine kinases and the Hedgehog pathway, respectively, can modulate signaling pathways that potentially intersect with the regulatory mechanisms of LOC653550. Bortezomib impacts protein turnover by inhibiting the proteasome, which could lead to an accumulation of proteins including LOC653550, if it is normally targeted for degradation. Retinoic Acid, all trans affects gene expression through the retinoic acid receptor-mediated pathway, offering another potential route to indirectly influence LOC653550 expression. Celecoxib, by inhibiting COX-2, can affect inflammatory signaling pathways and thus potentially the function of LOC653550 if it plays a role in inflammatory responses. DAPT, as a γ-secretase inhibitor, can impact the Notch signaling pathway, potentially affecting LOC653550 if it is part of this signaling cascade.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent PI3K inhibitor that can suppress the PI3K/Akt signaling pathway, potentially affecting LOC653550 if it is part of this pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
An inhibitor of MEK1/2 that can prevent the activation of the ERK pathway, possibly affecting LOC653550 if it is involved in cell growth signaling. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
A histone deacetylase inhibitor that can change chromatin structure and gene expression, potentially influencing LOC653550 if it is regulated by acetylation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that can suppress cell growth and proliferation signals, possibly affecting LOC653550 if it is involved in these processes. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) that can disrupt calcium homeostasis, potentially influencing LOC653550 if calcium signaling regulates its activity. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
A tyrosine kinase inhibitor that can inhibit Bcr-Abl and c-Kit, potentially affecting LOC653550 if it is modulated by these kinases. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $92.00 $204.00 | 19 | |
A Hedgehog signaling pathway inhibitor that can interfere with cellular signaling pathways, possibly affecting LOC653550 if it is part of this pathway. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can lead to the accumulation of ubiquitinated proteins, potentially affecting LOC653550 if it is subject to proteasomal degradation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A modulator of gene expression through retinoic acid receptors, potentially affecting LOC653550 if it is regulated by these pathways. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
A γ-secretase inhibitor that can interfere with Notch signaling, potentially affecting LOC653550 if the Notch pathway regulates it. | ||||||