LOC646285 Inhibitors
Wortmannin and U0126, for instance, by targeting PI3K and MEK1/2 respectively, could affect the phosphorylation status of LOC646285 or proteins that regulate LOC646285, thereby modulating its activity. SP600125 and MG132 could alter the JNK signaling pathway and ubiquitin-proteasome system, affecting the stability and turnover of LOC646285. NSC 23766 and Thapsigargin could impede Rac1 activity and calcium homeostasis, which may be critical for the proper functioning or localization of LOC646285.
Moreover, compounds such as KN-93 and PP2 could impact calcium/calmodulin-dependent processes and Src family kinase-related signaling, which in turn could influence the activity or regulation of LOC646285. LY83583's inhibition of guanylate cyclase and PD 169316's targeting of p38 MAPK could change the cGMP signaling and stress response pathways, potentially impacting the roles that LOC646285 plays within these contexts. Lastly, SB431542 could influence the TGF-β signaling pathway, which might be crucial for the function or regulation of LOC646285.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, potentially affecting proteins regulated by PI3K/Akt signaling. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
Inhibits MEK1/2, possibly affecting proteins downstream of the MAPK/ERK pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially altering the activity of proteins involved in the JNK signaling pathway. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor, potentially altering the degradation rate of proteins and affecting multiple signaling pathways. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
Pan-caspase inhibitor, potentially affecting proteins involved in apoptotic pathways. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
Inhibits Rac1, potentially affecting proteins involved in cytoskeletal organization and cell migration. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
SERCA pump inhibitor, potentially affecting calcium signaling and proteins regulated by calcium homeostasis. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibits CaMKII, potentially affecting proteins regulated by calcium/calmodulin-dependent processes. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
Src family kinase inhibitor, potentially affecting proteins involved in Src related signaling pathways. | ||||||
PD 169316 | 152121-53-4 | sc-204168 sc-204168A sc-204168B sc-204168C | 1 mg 5 mg 10 mg 25 mg | $86.00 $153.00 $275.00 $452.00 | 3 | |
Inhibits p38 MAPK, potentially altering the activity of proteins involved in the p38 MAPK stress response pathway. | ||||||