LOC642483 Inhibitors
Compounds like Wortmannin and LY294002 are potent inhibitors of PI3K, which can suppress AKT signaling, a crucial pathway for regulating various cellular functions including metabolism, survival, and growth. Rapamycin can specifically inhibit mTOR, another key kinase for cell growth and protein synthesis. Cyclosporin A's inhibition of calcineurin can prevent the activation of NFAT, a transcription factor that modulates gene expression and protein function.
Histone deacetylase inhibitors such as Trichostatin A can affect gene expression by altering chromatin structure and subsequently influencing protein synthesis. Calcium channel blockers like Nifedipine can modulate the calcium signaling pathways, which are vital for the function of numerous calcium-dependent proteins. Y-27632's inhibition of ROCK affects the dynamics of the actin cytoskeleton, potentially influencing proteins associated with cellular structure and motility. PD98059 can disrupt the ERK signaling pathway, which is involved in the regulation of various cellular activities, including protein function. SB431542 can hinder TGF-β signaling, which is crucial for cellular differentiation and proliferation. KN-93's inhibition of CaM kinase II affects calcium signaling and can alter the function of proteins regulated by this kinase.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor that can affect downstream AKT signaling, potentially altering functions of proteins regulated by this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can modulate the mTOR signaling pathway affecting protein synthesis and cell growth. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
An inhibitor of calcineurin leading to inhibition of NFAT translocation which can alter gene expression and protein function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
A histone deacetylase inhibitor that can change chromatin structure and affect gene expression, influencing protein synthesis. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
A calcium channel blocker that can alter intracellular calcium levels, potentially affecting proteins that are calcium-dependent. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor that can affect actin cytoskeleton dynamics, which may influence proteins associated with this structure. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, which can disrupt ERK signaling and can alter functions of proteins regulated by this pathway. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
An inhibitor of TGF-β receptor kinase that can hinder TGF-β signaling, potentially impacting protein function that is TGF-β dependent. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
An inhibitor of CaM kinase II which can affect calcium signaling and can alter the function of proteins regulated by this kinase. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $63.00 $114.00 $218.00 $349.00 | 74 | |
An EGFR inhibitor that can affect tyrosine kinase signaling, potentially influencing protein function downstream of EGFR. | ||||||