LOC390811 Inhibitors
LOC390811 inhibitor compounds such as Staurosporine and KN-93 belong to kinase inhibitors which target the catalytic activity of kinases that may phosphorylate LOC390811, influencing its activity state and function. LY294002, Wortmannin, and Rapamycin are inhibitors that act on PI3K and mTOR, respectively, both of which are central nodes in signaling pathways that regulate a vast array of cellular functions, including those associated with proteins like LOC390811. Disruption of these pathways can consequently alter the activity of LOC390811.
PD98059, U0126, and SB203580 are inhibitors that affect the MAPK signaling cascade, a pathway known to play a pivotal role in the regulation of protein functions through phosphorylation. JNK inhibitor SP600125 and Src inhibitor PP2 target different kinases that could modify the phosphorylation status of LOC390811 or of transcription factors that regulate its expression. Y-27632, a ROCK inhibitor, can influence the dynamics of the actin cytoskeleton, affecting cellular processes that may involve LOC390811. Lastly, Trichostatin A, by altering chromatin structure and gene expression, can impact the transcriptional regulation of LOC390811.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A broad-spectrum kinase inhibitor that can inhibit protein kinases which may phosphorylate LOC390811, affecting its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that can alter PI3K/AKT signaling, potentially modifying the function of proteins influenced by this pathway, including LOC390811. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
A MEK inhibitor that can disrupt the MAPK/ERK pathway, potentially affecting the phosphorylation status and function of LOC390811. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can alter protein synthesis and other processes that are essential for the function of numerous proteins, possibly including LOC390811. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor that can affect proteins regulated by stress-activated pathways, possibly including LOC390811. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which can modify the activity of proteins involved in the AP-1 signaling pathway, potentially including LOC390811. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
A PI3K inhibitor that can disrupt signaling pathways and processes in which LOC390811 may be involved. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
A selective inhibitor of CaMKII, a kinase that can influence calcium signaling pathways and the activity of proteins like LOC390811. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
An Src family kinase inhibitor that can alter signaling pathways, potentially affecting the phosphorylation and function of LOC390811. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor that can affect actin cytoskeleton dynamics and related signaling, which may influence the function of LOC390811. | ||||||