Date published: 2026-4-1

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LOC388849 Inhibitors

The protein "coiled-coil domain containing 188" (CCDC188) is a member of the CCDC family of proteins, which are named for the presence of coiled-coil domains within their structure. These domains are characterized by a heptad repeat pattern of amino acids that form an alpha-helical structure, with two or more of these helices intertwining to create a stable coiled-coil.

CCDC188, like other proteins in this family, likely participates in a variety of cellular processes involving protein-protein interactions. The coiled-coil motif is known to facilitate the assembly of multi-protein complexes, which are crucial in diverse cellular functions such as intracellular trafficking, cell division, signal transduction, and the regulation of gene expression.While the specific functions of CCDC188 may not be fully characterized, its structural features suggest a role in maintaining the architecture of certain protein complexes or scaffolds, potentially impacting cellular organization and communication. The coiled-coil domain is often involved in the formation of cytoskeletal structures, vesicle transport, and the organization of the nuclear envelope, among other functions.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

A potent inhibitor of phosphoinositide 3-kinases (PI3K), which may influence signaling pathways indirectly related to CCDC188.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Another PI3K inhibitor, which could impact pathways that may be relevant to the function of coiled-coil domain proteins like CCDC188.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

A p38 MAP kinase inhibitor, potentially affecting signaling pathways that could intersect with CCDC188-related processes.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

An inhibitor of c-Jun N-terminal kinase (JNK), which might influence signaling pathways indirectly associated with CCDC188.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

A ROCK inhibitor, affecting cytoskeletal dynamics that coiled-coil domain proteins might be involved in.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

An inhibitor of MAP kinase kinase (MEK), which could indirectly affect CCDC188-related signaling.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor, which might indirectly impact CCDC188 by modulating cell growth and protein synthesis pathways.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

An inhibitor of protein transport within cells, which could indirectly affect CCDC188.

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

An immunosuppressant that inhibits calcineurin, potentially affecting pathways relevant to CCDC188.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

A SERCA pump inhibitor, affecting calcium homeostasis, potentially influencing CCDC188-related processes.