LOC388849 Activators

Coiled-coil domain containing 188 (CCDC188) is a protein that is encoded by the CCDC188 gene in humans. As suggested by its name, this protein is characterized by the presence of a coiled-coil domain, which is a structural motif often involved in mediating protein-protein interactions. Coiled-coil domains consist of alpha-helices that are wound together like the strands of a rope, and this structure is commonly involved in the formation of protein oligomers.The coiled-coil domain within CCDC188 likely contributes to its ability to interact with other proteins, facilitating a range of cellular functions. Proteins with coiled-coil domains are involved in many different biological processes, including but not limited to vesicle transport, gene regulation, and cytoskeletal organization. They are critical for maintaining the structural integrity of various cellular structures, such as the mitotic spindle during cell division.

While the specificCoiled-coil domain containing 188 (CCDC188) is a protein that derives its name from the hallmark structural motif it contains: the coiled-coil domain. This motif is characterized by two or more alpha-helices wound around each other, resembling the twists of a rope, and is known to mediate protein-protein interactions, oligomerization, and the formation of functional protein complexes.The presence of the coiled-coil domain in CCDC188 suggests that it participates in processes that require specific and stable interactions with other proteins. These interactions can be pivotal in a variety of cellular mechanisms, such as intracellular trafficking, scaffolding, signaling, and the maintenance of cellular structures like the cytoskeleton.